Evidence map›Paper›PMID 28620086›Full record

ArticleG3 (Bethesda, Md.)2017

A Genetic Screen Reveals an Unexpected Role for Yorkie Signaling in JAK/STAT-Dependent Hematopoietic Malignancies in

Abigail M Anderson, Alessandro A Bailetti, Elizabeth Rodkin, Atish De, Erika A Bach

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Notch Signaling in Drosophila Tumor Models.Advances in experimental medicine and biology · 2025
    Review
  5. Mitochondrial AAAFrontiers in cell and developmental biology · 2025
    Article
  6. Modelling Cancer in Drosophila: Exploration to Personalised Medicine.Advances in experimental medicine and biology · 2025
    Review
  7. Review
  8. Review
  9. Tumor models in various Drosophila tissues.WIREs mechanisms of disease · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Frontiers in genetics · 2019
    Review
  15. Hippo Signaling in Cancer: Lessons FromFrontiers in cell and developmental biology · 2019
    Review
  16. Review
  17. AnOpen biology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abigail M AndersonDepartment of Biochemistry and Molecular Pharmacology, The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, New York University School of Medicine, New York 10016.
Alessandro A BailettiDepartment of Biochemistry and Molecular Pharmacology, The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, New York University School of Medicine, New York 10016.
Elizabeth RodkinDepartment of Biochemistry and Molecular Pharmacology, The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, New York University School of Medicine, New York 10016.
Atish DeDepartment of Biochemistry and Molecular Pharmacology, The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, New York University School of Medicine, New York 10016.
Erika A BachDepartment of Biochemistry and Molecular Pharmacology, The Helen L. and Martin S. Kimmel Center for Stem Cell Biology, New York University School of Medicine, New York 10016 erika.bach@nyu.edu.ORCID 0000-0002-5997-4489
New York University · US

Funding

TRAINING PROGRAM IN MOLECULAR ONCOLOGY &IMMUNOLOGYT32CA009161 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARROLL, WILLIAM L., LEVY, DAVID E · 1985 to 2020
$13.3M
Eludicating the Molecular Mechanisms That Regulate Stem Cell Numbers in VivoR01GM085075 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BACH, ERIKA A · 2009 to 2023
$4.3M
Drosophila as a low complexity model for human neoplasmsF32CA200075 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANDERSON, ABIGAIL MARIE · 2015 to 2015
$56k
NCI NIH HHS F32 CA200075NCI NIH HHS T32 CA009161NIGMS NIH HHS R01 GM085075
6 · The paper itself

Abstract

A gain-of-function mutation in the tyrosine kinase JAK2 (

Indexed as

Genetic TestingSignal TransductionAllelesAnimalsCell ProliferationDrosophila melanogasterDrosophila ProteinsHematologic NeoplasmsHematopoiesisHemocytesJanus KinasesMutationNuclear ProteinsTrans-ActivatorsTumor BurdenUp-RegulationDrosophila ProteinsJanus KinasesNuclear ProteinsTrans-ActivatorsYAP-Signaling ProteinsYki protein, DrosophilabantamDrosophila melanogasterexpandedhippohopscotchMycStat92Ewartsyorkie

Identifiers

PMID28620086
PMCPMC5555452
OpenAlexW2626478697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.