Evidence map›Paper›PMID 28620084›Full record

ArticleG3 (Bethesda, Md.)2017

Multidimensional Genetic Analysis of Repeated Seizures in the Hybrid Mouse Diversity Panel Reveals a Novel Epileptogenesis Susceptibility Locus.

Russell J Ferland, Jason Smith, Dominick Papandrea, Jessica Gracias, Leah Hains, Sridhar B Kadiyala, Brittany O'Brien, Eun Yong Kang, Barbara S Beyer, Bruce J Herron

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Russell J FerlandDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York 12208 ferlanr@mail.amc.edu bruce.herron@health.ny.gov.ORCID 0000-0002-8044-2479
Jason SmithWadsworth Center, New York State Department of Health, Albany, New York 12201.
Dominick PapandreaDepartment of Biological Sciences, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180.
Jessica GraciasDepartment of Biomedical Sciences, School of Public Health, University at Albany, State University of New York, New York 12201.
Leah HainsWadsworth Center, New York State Department of Health, Albany, New York 12201.
Sridhar B KadiyalaDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York 12208.
Brittany O'BrienDepartment of Biomedical Sciences, School of Public Health, University at Albany, State University of New York, New York 12201.
Eun Yong KangDepartment of Computer Science, University of California, Los Angeles, California 90095.
Barbara S BeyerDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York 12208.
Bruce J HerronWadsworth Center, New York State Department of Health, Albany, New York 12201 ferlanr@mail.amc.edu bruce.herron@health.ny.gov.ORCID 0000-0002-0233-9513
Wadsworth Center · USAlbany Medical Center Hospital · USRensselaer Polytechnic Institute · USUniversity at Albany, State University of New York · USUniversity of California, Los Angeles · US

Funding

Genetic Mechanisms of EpileptogenesisR01NS064283 · NINDS · ALBANY MEDICAL COLLEGE · PI FERLAND, RUSSELL JAMES · 2011 to 2014
$1.3M
NINDS NIH HHS R01 NS064283
6 · The paper itself

Abstract

Epilepsy has many causes and comorbidities affecting as many as 4% of people in their lifetime. Both idiopathic and symptomatic epilepsies are highly heritable, but genetic factors are difficult to characterize among humans due to complex disease etiologies. Rodent genetic studies have been critical to the discovery of seizure susceptibility loci, including

Indexed as

Genetic LociGenetic Predisposition to DiseaseGenetic VariationAllelesAnimalsBrainChromosomes, MammalianCrosses, GeneticDisease Models, AnimalEpilepsyEpistasis, GeneticFemaleFlurothylGenome-Wide Association StudyKindling, NeurologicMaleFlurothylcomplex traitsepilepsygeneticsneuronal plasticitypreclinical model

Identifiers

PMID28620084
PMCPMC5555461
OpenAlexW2625412183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.