Evidence map›Paper›PMID 28619956›Full record

Observational studyThe European respiratory journal2017

A longitudinal modelling study estimates acute symptoms of community acquired pneumonia recover to baseline by 10 days.

Daniel G Wootton, Laura Dickinson, Henry Pertinez, Joanne Court, Odiri Eneje, Lynne Keogan, Laura Macfarlane, Sarah Wilks, Jane Gallagher, Mark Woodhead and 2 more

Abstract readObservational Study
In one paragraph

Observational study in The European respiratory journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Pneumonia.Nature reviews. Disease primers · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Daniel G WoottonInstitute of Infection and Global Health, University of Liverpool, Liverpool, UK dwootton@liverpool.ac.uk.
Laura DickinsonDept of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Henry PertinezDept of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Joanne CourtDept of Respiratory Research, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
Odiri EnejeDept of Respiratory Research, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
Lynne KeoganDept of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
Laura MacfarlaneDept of Respiratory Research, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
Sarah WilksDept of Respiratory Research, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
Jane GallagherIndependent patient representative.
Mark WoodheadDept of Respiratory Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Stephen B GordonDept of Respiratory Research, Aintree University Hospital NHS Foundation Trust, Liverpool, UK.
Peter J DiggleCHICAS, Lancaster University Medical School, Lancaster University, Lancaster, UK.

Funding

Department of Health DRF-2010-03-154
6 · The paper itself

Abstract

Our aims were to address three fundamental questions relating to the symptoms of community-acquired pneumonia (CAP): Do patients completely recover from pneumonia symptoms? How long does this recovery take? Which factors influence symptomatic recovery?We prospectively recruited patients at two hospitals in Liverpool, UK, into a longitudinal, observational cohort study and modelled symptom recovery from CAP. We excluded patients with cancer, immunosuppression or advanced dementia, and those who were intubated or palliated from admission. We derived a statistical model to describe symptom patterns.We recruited 169 (52% male) adults. Multivariable analysis demonstrated that the time taken to recover to baseline was determined by the initial severity of symptoms. Severity of symptoms was associated with comorbidity and was inversely related to age. The pattern of symptom recovery was exponential and most patients' symptoms returned to baseline by 10 days.These results will inform the advice given to patients regarding the resolution of their symptoms. The recovery model described here will facilitate the use of symptom recovery as an outcome measure in future clinical trials.

Indexed as

Community-Acquired InfectionsModels, StatisticalPneumoniaAdultAgedCohort StudiesComorbidityFemaleHospitalizationHumansMaleMiddle AgedOutcome Assessment, Health CarePatient AcuityRecovery of FunctionSymptom Assessment

Identifiers

PMID28619956
PMCPMC5898948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.