ArticleGenome research2017
The house fly Y Chromosome is young and minimally differentiated from its ancient X Chromosome partner.
Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Evolution of Sex-linked Genes and the Role of Pericentromeric Regions in Sex Chromosomes: Insights from Diploid Willows.Molecular biology and evolution · 2024Article
- Article
- Divergent evolution of male-determining loci on proto-Y chromosomes of the housefly.Nature communications · 2024Article
- The Role of Transposable Elements in Sexual Development.Frontiers in behavioral neuroscience · 2022Review
- Thermal tolerance and preference are both consistent with the clinal distribution of house fly proto-Y chromosomes.Evolution letters · 2021Article
- Heterogeneous Histories of Recombination Suppression on Stickleback Sex Chromosomes.Molecular biology and evolution · 2021Article
- How did the guppy Y chromosome evolve?PLoS genetics · 2021Article
- Review
- The Dryas iulia Genome Supports Multiple Gains of a W Chromosome from a B Chromosome in Butterflies.Genome biology and evolution · 2021Article
- Gene-Level, but Not Chromosome-Wide, Divergence between a Very Young House Fly Proto-Y Chromosome and Its Homologous Proto-X Chromosome.Molecular biology and evolution · 2021Article
- The Theory and Applications of Measuring Broad-Range and Chromosome-Wide Recombination Rate from Allele Frequency Decay around a Selected Locus.Molecular biology and evolution · 2020Article
- Sex Chromosome Evolution in Muscid Flies.G3 (Bethesda, Md.) · 2020Article
- Differential Gene Expression between Fungal Mating Types Is Associated with Sequence Degeneration.Genome biology and evolution · 2020Article
- The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence.BMC biology · 2019Article
- Molecular and evolutionary dynamics of animal sex-chromosome turnover.Nature ecology & evolution · 2019Review
- Minimal Effects of Proto-Genetics · 2019Article
- Sex and the TEs: transposable elements in sexual development and function in animals.Mobile DNA · 2019Review
- Evolutionary and developmental dynamics of sex-biased gene expression in common frogs with proto-Y chromosomes.Genome biology · 2018Article
- Review
- Shared and Species-Specific Patterns of Nascent Y Chromosome Evolution in Two Guppy Species.Genes · 2018Article
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Canonical ancient sex chromosome pairs consist of a gene rich X (or Z) Chromosome and a male-limited (or female-limited) Y (or W) Chromosome that is gene poor. In contrast to highly differentiated sex chromosomes, nascent sex chromosome pairs are homomorphic or very similar in sequence content. Nascent sex chromosomes can arise if an existing sex chromosome fuses to an autosome or an autosome acquires a new sex-determining locus/allele. Sex chromosomes often differ between closely related species and can even be polymorphic within species, suggesting that nascent sex chromosomes arise frequently over the course of evolution. Previously documented sex chromosome transitions involve changes to both members of the sex chromosome pair (X and Y, or Z and W). The house fly has sex chromosomes that resemble the ancestral fly karyotype that originated ∼100 million yr ago; therefore, the house fly is expected to have X and Y Chromosomes with different gene content. We tested this hypothesis using whole-genome sequencing and transcriptomic data, and we discovered little evidence for genetic differentiation between the X and Y in house fly. We propose that the house fly has retained the ancient X Chromosome, but the ancestral Y was replaced by an X Chromosome carrying a new male determining gene. Our proposed hypothesis provides a mechanism for how one member of a sex chromosome pair can experience evolutionary turnover while the other member remains unaffected.
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