Evidence map›Paper›PMID 28619834›Full record

ArticleAJNR. American journal of neuroradiology2017

Temporal and Spatial Variances in Arterial Spin-Labeling Are Inversely Related to Large-Artery Blood Velocity.

A D Robertson, G Matta, V S Basile, S E Black, C K Macgowan, J A Detre, B J MacIntosh

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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  11. Spatial coefficient of variation in pseudo-continuous arterial spin labeling cerebral blood flow images as a hemodynamic measure for cerebrovascular steno-occlusive disease: A comparativeJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

A D RobertsonFrom the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (A.D.R., G.M., S.E.B., B.J.M.) adrobert@sri.utoronto.ca.ORCID http://orcid.org/0000-0002-9095-9877
G MattaFrom the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (A.D.R., G.M., S.E.B., B.J.M.).ORCID http://orcid.org/0000-0002-5855-1425
V S BasileDivision of Neurology, Department of Medicine (V.S.B., S.E.B.), University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-5264-4869
S E BlackFrom the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (A.D.R., G.M., S.E.B., B.J.M.).ORCID http://orcid.org/0000-0001-7093-8289
C K MacgowanHospital for Sick Children (C.K.M.), Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-7016-0662
J A DetreDepartment of Neurology (J.A.D.), University of Pennsylvania, Philadelphia, Pennsylvania.ORCID http://orcid.org/0000-0002-8115-6343
B J MacIntoshFrom the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (A.D.R., G.M., S.E.B., B.J.M.).ORCID http://orcid.org/0000-0001-7300-2355
Sunnybrook Health Science Centre · CAUniversity of Toronto · CAHeart and Stroke Foundation · CAUniversity of Pennsylvania · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

background and purposeThe relationship between extracranial large-artery characteristics and arterial spin-labeling MR imaging may influence the quality of arterial spin-labeling-CBF images for older adults with and without vascular pathology. We hypothesized that extracranial arterial blood velocity can explain between-person differences in arterial spin-labeling data systematically across clinical populations. MATERIALS AND

methodsWe performed consecutive pseudocontinuous arterial spin-labeling and phase-contrast MR imaging on 82 individuals (20-88 years of age, 50% women), including healthy young adults, healthy older adults, and older adults with cerebral small vessel disease or chronic stroke infarcts. We examined associations between extracranial phase-contrast hemodynamics and intracranial arterial spin-labeling characteristics, which were defined by labeling efficiency, temporal signal-to-noise ratio, and spatial coefficient of variation.

resultsLarge-artery blood velocity was inversely associated with labeling efficiency (

conclusionsBetween-subject arterial spin-labeling variance was partially explained by extracranial velocity but not cross-sectional area. Choosing arterial spin-labeling timing parameters with on-line knowledge of blood velocity may improve CBF quantification.

Indexed as

Spin LabelsAdultAgedAged, 80 and overAgingAnatomy, Cross-SectionalBlood Flow VelocityCerebral ArteriesCerebrovascular CirculationFemaleHealthy VolunteersHemodynamicsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleSpin Labels

Identifiers

PMID28619834
PMCPMC7960433
OpenAlexW2626703541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.