Evidence map›Paper›PMID 28619822›Full record

ArticleDevelopment (Cambridge, England)2017

COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation.

Annabelle Suisse, DanQing He, Kevin Legent, Jessica E Treisman

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Annabelle SuisseHelen L. and Martin S. Kimmel Center at the Skirball Institute for Biomolecular Medicine and Department of Cell Biology, NYU School of Medicine, 540 First Avenue, New York, NY 10016, USA.
DanQing HeHelen L. and Martin S. Kimmel Center at the Skirball Institute for Biomolecular Medicine and Department of Cell Biology, NYU School of Medicine, 540 First Avenue, New York, NY 10016, USA.
Kevin LegentHelen L. and Martin S. Kimmel Center at the Skirball Institute for Biomolecular Medicine and Department of Cell Biology, NYU School of Medicine, 540 First Avenue, New York, NY 10016, USA.ORCID 0000-0001-8547-0914
Jessica E TreismanHelen L. and Martin S. Kimmel Center at the Skirball Institute for Biomolecular Medicine and Department of Cell Biology, NYU School of Medicine, 540 First Avenue, New York, NY 10016, USA jessica.treisman@med.nyu.edu.ORCID 0000-0002-7453-107X
New York University · US

Funding

Pattern formation in the eye discR01EY013777 · NEI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI TREISMAN, JESSICA E · 2002 to 2017
$5.8M
NEI NIH HHS R01 EY013777
6 · The paper itself

Abstract

The COP9 signalosome removes Nedd8 modifications from the Cullin subunits of ubiquitin ligase complexes, reducing their activity. Here, we show that mutations in the

Indexed as

AnimalsAnimals, Genetically ModifiedCOP9 Signalosome ComplexCullin ProteinsDrosophila melanogasterDrosophila ProteinsErbB ReceptorsEyeFemaleGenes, InsectHMGB ProteinsMaleMAP Kinase Signaling SystemModels, BiologicalMultiprotein ComplexesMutationcic protein, DrosophilaCOP9 Signalosome ComplexCullin 1Cullin ProteinsDrosophila ProteinsEgfr protein, DrosophilaErbB ReceptorsHMGB ProteinsMultiprotein ComplexesPeptide HydrolasesProtein SubunitsReceptors, Invertebrate PeptideRepressor ProteinsCapicuaCOP9 signalosomeDrosophila melanogasterEGFRNedd8Ubiquitin ligaseWing disc

Identifiers

PMID28619822
PMCPMC5536928
OpenAlexW2624859757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.