ArticleAmerican journal of preventive medicine2017
Major Physical Health Conditions and Risk of Suicide.
Article in American journal of preventive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 6 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
118 citing papers in PubMed, 6 syntheses or guidelines pooled it, 259 citations in OpenAlex.
- Suicide risk in patients undergoing hemodialysis: a systematic review and meta-analysis of prevalence.Renal failure · 2025Pooled it
- Suicide and Suicidal Ideation Among Survivors of Childhood Cancer: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Assessing suicide risk in patients with heart failure: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- The Pooled Prevalence of Attributed Factors of Suicide in Iran: A Systematic Review and Meta-analysis.Archives of Iranian medicine · 2025Pooled it
- GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.The American journal of psychiatry · 2023Pooled it
- Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023Pooled it
- Suicidal Thoughts and Behaviors Do Not Influence Veterans' Alcohol Use Disorder or Posttraumatic Stress Disorder Recovery Trajectories in a Randomized Controlled Trial.Journal of studies on alcohol and drugs · 2026Trial
- Trial
- Physical Health Conditions Among Suicide Decedents: National Violent Death Reporting System, U.S., 2020-2023.American journal of preventive medicine · 2026Article
- Depression, non-medical pain prescriptions, and suicidal behavior in cancer survivors.Journal of cancer survivorship : research and practice · 2026Article
- Association between maternal infections during pregnancy and offspring suicide risk: A national cohort study.Molecular psychiatry · 2026Article
- Positive Mental Health Screens in the Veterans Health Administration, 2021 to 2024.JAMA network open · 2026Article
- Obesity and Suicide Behavior in Young Latina Adults of Mexican Heritage: The Mediating Influences of Sleep Problems, Health Problems, and Dissatisfaction with Personal Appearance.Behavioral sciences (Basel, Switzerland) · 2026Article
- Comparing Risk Prediction for Suicide Attempts and Deaths After Emergency Department Visits for Individuals With Mental Health Disorders.The Journal of clinical psychiatry · 2026Article
- A retrospective cohort study of clinical characteristics and healthcare contacts in Sweden prior to suicide in individuals with heart disease.BMC primary care · 2026Article
- A phenome-wide association and Mendelian randomization study for suicide attempt within UK Biobank.Molecular psychiatry · 2026Article
- Mediating mechanisms of the association between prenatal tobacco exposure and adolescent suicide attempt: A 17-year longitudinal study.Psychological medicine · 2026Article
- Self-Injury Mortality: Global Ascertainment and Prevention.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026Review
- Chronic health condition and risk of suicidal behaviours in two hospitals in Ghana.BMC public health · 2025Article
- A pragmatic and ethical guide for addressing life-sustaining treatments in patients with suicidal thoughts or behaviors.Journal of hospital medicine · 2025Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 6 institutions in 1 country.
Funding
Abstract
introductionMost individuals make healthcare visits before suicide, but many do not have a diagnosed mental health condition. This study seeks to investigate suicide risk among patients with a range of physical health conditions in a U.S. general population sample and whether risk persists after adjustment for mental health and substance use diagnoses.
methodsThis study included 2,674 individuals who died by suicide between 2000 and 2013 along with 267,400 controls matched on year and location in a case-control study conducted in 2016 across eight Mental Health Research Network healthcare systems. A total of 19 physical health conditions were identified using diagnostic codes within the healthcare systems' Virtual Data Warehouse, including electronic health record and insurance claims data, during the year before index date.
resultsSeventeen physical health conditions were associated with increased suicide risk after adjustment for age and sex (p<0.001); nine associations persisted after additional adjustment for mental health and substance use diagnoses. Three conditions had a more than twofold increased suicide risk: traumatic brain injury (AOR=8.80, p<0.001); sleep disorders; and HIV/AIDS. Multimorbidity was present in 38% of cases versus 15.5% of controls, and represented nearly a twofold increased risk for suicide.
conclusionsAlthough several individual conditions, for example, traumatic brain injury, were associated with high risk of suicide, nearly all physical health conditions increased suicide risk, even after adjustment for potential confounders. In addition, having multiple physical health conditions increased suicide risk substantially. These data support suicide prevention based on the overall burden of physical health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.