Evidence map›Paper›PMID 28618772›Full record

Trial reportThe Korean journal of internal medicine2017

Efficacy and safety of pitavastatins in patients with acute myocardial infarction: Livalo in Acute Myocardial Infarction Study (LAMIS) II.

Young Joon Hong, Myung Ho Jeong, Jang Ho Bae, Seok Kyu Oh, Seung Woon Rha, Seung Ho Hur, Sung Yun Lee, Sang Wook Kim, Kwang Soo Cha, In Ho Chae and 2 more

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in The Korean journal of internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Pitavastatin: Coronary Atherosclerotic Plaques Changes and Cardiovascular Prevention.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Young Joon HongDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Myung Ho JeongDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Korea.
Jang Ho BaeDepartment of Cardiology, Konyang University Hospital, Daejeon, Korea.
Seok Kyu OhDepartment of Cardiology, Wonkwang University Hospital, Iksan, Korea.
Seung Woon RhaDepartment of Cardiology, Korea University Guro Hospital, Seoul, Korea.
Seung Ho HurDepartment of Cardiology, Keimyung University Dongsan Medical Center, Daegu, Korea.
Sung Yun LeeDepartment of Cardiology, Inje University Ilsan Paik Hospital, Goyang, Korea.
Sang Wook KimDepartment of Cardiology, Chung-Ang University Hospital, Seoul, Korea.
Kwang Soo ChaDepartment of Cardiology, Pusan National University Hospital, Busan, Korea.
In Ho ChaeDepartment of Cardiology, Seoul National University Bundang Hospital, Seongnam, Korea.
Tae Hoon AhnDepartment of Cardiology, Gachon University Gil Medical Center, Incheon, Korea.
Kee Sik KimDepartment of Cardiology, Daegu Catholic University Medical Center, Daegu, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsWe evaluated the efficacy and safety and influence on glucose tolerance by different doses of pitavastatins in acute myocardial infarction (AMI) patients.

methodsConsecutive 1,101 AMI patients who were enrolled in Livalo in Acute Myocardial Infarction Study (LAMIS)-II were randomly assigned to receive either 2 mg of pitavastatin or 4 mg of pitavastatin orally per day. Primary efficacy endpoint was composite of cardiac death, nonfatal myocardial infarction, target-lesion revascularization, and hospitalization for unstable angina, heart failure or arrhythmic events at 12-month.

resultsThere was no significant difference in primary efficacy endpoint between 2 mg and 4 mg groups (9.07% vs. 9.13%,

conclusionsAlthough LDL-C was reduced more significantly by using 4 mg of pitavastatin compared to 2 mg of pitavastatin, the event rate was comparable without adverse effects on glucose tolerance in both groups in AMI patients who were enrolled in LAMIS-II.

Indexed as

AgedBlood GlucoseFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedMyocardial InfarctionQuinolinesSecondary PreventionBlood GlucoseHydroxymethylglutaryl-CoA Reductase InhibitorspitavastatinQuinolinesAtherosclerosisHydroxymethylglutaryl-CoA reductase inhibitorsLipidsMyocardial infarction

Identifiers

PMID28618772
PMCPMC5511934

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.