ArticleBrain and cognition2017
Diffusion tensor MRI tractography reveals increased fractional anisotropy (FA) in arcuate fasciculus following music-cued motor training.
Article in Brain and cognition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploration of Brain Changes Due to a Targeted Ballet Program in Multiple Sclerosis
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Who cites it
30 citing papers in PubMed.
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- Musical training is associated with cognitive outcomes and white matter microstructure in middle childhood.Developmental cognitive neuroscience · 2026Article
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- Topography of Functional Organization of Beat Perception in Human Premotor Cortex: Causal Evidence From a Transcranial Magnetic Stimulation (TMS) Study.Human brain mapping · 2025Article
- White matter quantitative anomalies and clinical outcome in drug-resistant epilepsies.Psychoradiology · 2025Article
- Cognitive and motor abilities predict auditory-cued finger tapping in a dual task.Frontiers in neuroscience · 2025Article
- Musical Sophistication and Multilingualism: Effects on Arcuate Fasciculus Characteristics.Human brain mapping · 2024Article
- White and Gray Matter Abnormality in Burning Mouth Syndrome Evaluated with Diffusion Tensor Imaging and Neurite Orientation Dispersion and Density Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Article
- Investigating female versus male differences in white matter neuroplasticity associated with complex visuo-motor learning.Scientific reports · 2024Article
- Altered Brain Structure in Hemifacial Spasm Patients: A Multimodal Brain Structure Study.International journal of general medicine · 2024Article
- Sex differences in patterns of white matter neuroplasticity after balance training in young adults.Frontiers in human neuroscience · 2024Article
- Increased functional connectivity in the right dorsal auditory stream after a full year of piano training in healthy older adults.Scientific reports · 2023Article
- Mathematical Optimisation of Magnetic Nanoparticle Diffusion in the Brain White Matter.International journal of molecular sciences · 2023Article
- A narrative review of the anatomy and function of the white matter tracts in language production and comprehension.Frontiers in human neuroscience · 2023Review
- EPI susceptibility correction introduces significant differences far from local areas of high distortion.Magnetic resonance imaging · 2022Article
- Integrating music-based interventions with Gamma-frequency stimulation: Implications for healthy ageing.The European journal of neuroscience · 2022Review
- Structural connectivity and subcellular changes after antidepressant doses of ketamine and Ro 25-6981 in the rat: an MRI and immuno-labeling study.Brain structure & function · 2021Article
- Multilevel rhythms in multimodal communication.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
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Authors and funding
5 authors.
Funding
Abstract
Auditory cues are frequently used to support movement learning and rehabilitation, but the neural basis of this behavioural effect is not yet clear. We investigated the microstructural neuroplasticity effects of adding musical cues to a motor learning task. We hypothesised that music-cued, left-handed motor training would increase fractional anisotropy (FA) in the contralateral arcuate fasciculus, a fibre tract connecting auditory, pre-motor and motor regions. Thirty right-handed participants were assigned to a motor learning condition either with (Music Group) or without (Control Group) musical cues. Participants completed 20minutes of training three times per week over four weeks. Diffusion tensor MRI and probabilistic neighbourhood tractography identified FA, axial (AD) and radial (RD) diffusivity before and after training. Results revealed that FA increased significantly in the right arcuate fasciculus of the Music group only, as hypothesised, with trends for AD to increase and RD to decrease, a pattern of results consistent with activity-dependent increases in myelination. No significant changes were found in the left ipsilateral arcuate fasciculus of either group. This is the first evidence that adding musical cues to movement learning can induce rapid microstructural change in white matter pathways in adults, with potential implications for therapeutic clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.