ArticleUltrasonics2017
Noninvasive measurement of wave speed of porcine cornea in ex vivo porcine eyes for various intraocular pressures.
Article in Ultrasonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Ex vivo, in vivo and in silico studies of corneal biomechanics: a systematic review.Physical and engineering sciences in medicine · 2024Pooled it
- Evaluation of the iFalconBMC veterinary research · 2026Article
- A noninvasive ultrasound vibro-elastography technique for assessing ocular lesions.Ultrasonics · 2025Article
- Exploring the Feasibility of Estimating Intraocular Pressure Using Vibrational Response of the Eye: A Methodological Approach.Sensors (Basel, Switzerland) · 2024Article
- A review of human cornea finite element modeling: geometry modeling, constitutive modeling, and outlooks.Frontiers in bioengineering and biotechnology · 2024Review
- Nonlinear fourth-order elastic characterization of the cornea using torsional wave elastography.Physical and engineering sciences in medicine · 2023Article
- Quantitative Evaluation of In Vivo Corneal Biomechanical Properties after SMILE and FLEx Surgery by Acoustic Radiation Force Optical Coherence Elastography.Sensors (Basel, Switzerland) · 2022Article
- Assessing Corneal Endothelial Damage Using Terahertz Time-Domain Spectroscopy and Support Vector Machines.Sensors (Basel, Switzerland) · 2022Article
- Torsional wave elastography to assess the mechanical properties of the cornea.Scientific reports · 2022Article
- Comparison of Corneal Wave Speed and Ocular Rigidity in Normal and Glaucomatous Eyes.Journal of glaucoma · 2021Article
- Layer-specific ultrasound elastography using a multi-layered shear wave dispersion model for assessing the viscoelastic properties.Physics in medicine and biology · 2021Article
- A pilot study for intraocular pressure measurements based on vibroacoustic parameters.Scientific reports · 2021Article
- Ultrasound Surface Wave Elastography for Assessing Scleroderma.Ultrasound in medicine & biology · 2020Article
- An ex vivo technique for quantifying mouse lung injury using ultrasound surface wave elastography.Journal of biomechanics · 2020Article
- An Ultrasound Vibro-Elastography Technique for Assessing Papilledema.Ultrasound in medicine & biology · 2019Article
- Article
- Lung Ultrasound Surface Wave Elastography for Assessing Interstitial Lung Disease.IEEE transactions on bio-medical engineering · 2019Article
- A quantitative method for measuring the changes of lung surface wave speed for assessing disease progression of interstitial lung disease.Ultrasound in medicine & biology · 2019Article
- Ultrasonic Microelastography to Assess Biomechanical Properties of the Cornea.IEEE transactions on bio-medical engineering · 2019Article
- The effect of pleural fluid layers on lung surface wave speed measurement: Experimental and numerical studies on a sponge lung phantom.Journal of the mechanical behavior of biomedical materials · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The objective of this study was to extend an ultrasound surface wave elastography (USWE) technique for noninvasive measurement of ocular tissue elastic properties. In particular, we aim to establish the relationship between the wave speed of cornea and the intraocular pressure (IOP). Normal ranges of IOP are between 12 and 22mmHg. Ex vivo porcine eye balls were used in this research. The porcine eye ball was supported by the gelatin phantom in a testing container. Some water was pour into the container for the ultrasound measurement. A local harmonic vibration was generated on the side of the eye ball. An ultrasound probe was used to measure the wave propagation in the cornea noninvasively. A 25 gauge butterfly needle was inserted into the vitreous humor of the eye ball under the ultrasound imaging guidance. The needle was connected to a syringe. The IOP was obtained by the water height difference between the water level in the syringe and the water level in the testing container. The IOP was adjusted between 5mmHg and 30mmHg with a 5mmHg interval. The wave speed was measured at each IOP for three frequencies of 100, 150 and 200Hz. Finite element method (FEM) was used to simulate the wave propagation in the corneal according to our experimental setup. A linear viscoelastic FEM model was used to compare the experimental data. Both the experiments and the FEM analyses showed that the wave speed of cornea increased with IOP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.