Evidence map›Paper›PMID 28618138›Full record

ArticleStem cells translational medicine2017

Expansion of Umbilical Cord Blood Aldehyde Dehydrogenase Expressing Cells Generates Myeloid Progenitor Cells that Stimulate Limb Revascularization.

David M Putman, Tyler T Cooper, Stephen E Sherman, Ayesh K Seneviratne, Mark Hewitt, Gillian I Bell, David A Hess

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Stem cells translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05253521 completednot on this mapstarted 2022, after this paper: background citation

The Role of South Asian vs European Origins on Circulating Regenerative Cell Exhaustion

TypeobservationalSponsorCanadian Medical and Surgical Knowledge Translation Research GroupRan2022 to 2023Enrolled120ConditionsDiabetes, Type 1 Diabetes, Type 2 Diabetes, Ischemic Heart Disease
NCT05410834 unknown statusnot on this mapstarted 2022, after this paper: background citation

The Characterization of Pro-vascular Regenerative Cell Exhaustion in Women With Polycystic Ovarian Syndrome

TypeobservationalSponsorCanadian Medical and Surgical Knowledge Translation Research GroupRan2022 to 2023Enrolled30ConditionsPolycystic Ovary Syndrome
NCT06108388 unknown statusnot on this mapstarted 2023, after this paper: background citation

Functional Investigation of Endothelial Function and Regenerative Cell Exhaustion in Type 2 Diabetes

TypeobservationalSponsorCanadian Medical and Surgical Knowledge Translation Research GroupRan2023 to 2026Enrolled90ConditionsDiabetes Mellitus, Type 2
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

David M PutmanMolecular Medicine Research Laboratories, Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada.
Tyler T CooperMolecular Medicine Research Laboratories, Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada.
Stephen E ShermanMolecular Medicine Research Laboratories, Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada.
Ayesh K SeneviratneMolecular Medicine Research Laboratories, Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada.
Mark HewittDepartment of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Gillian I BellMolecular Medicine Research Laboratories, Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada.
David A HessMolecular Medicine Research Laboratories, Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada.ORCID 0000-0003-2186-3166
Krembil Foundation · CARobarts Clinical Trials · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uncompromised by chronic disease-related comorbidities, human umbilical cord blood (UCB) progenitor cells with high aldehyde dehydrogenase activity (ALDH

Indexed as

Neovascularization, PhysiologicAldehyde DehydrogenaseAnimalsCell DifferentiationCells, CulturedCoculture TechniquesCulture Media, ConditionedExtremitiesHumansIschemiaMiceMice, Inbred NODMice, SCIDMyeloid Progenitor CellsStem Cell TransplantationUmbilical CordAldehyde DehydrogenaseCulture Media, ConditionedAldehyde dehydrogenaseAngiogenesisHematopoietic progenitor cell expansionPeripheral artery diseaseTransplantationUmbilical cord blood

Identifiers

PMID28618138
PMCPMC5689765
OpenAlexW2625845277

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.