Evidence map›Paper›PMID 28618099›Full record

ArticleCellular microbiology2017

EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity.

Rocio Tapia, Sarah E Kralicek, Gail A Hecht

Open access · bronzeAbstract read
In one paragraph

Article in Cellular microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. EspF of EnterohemorrhagicFrontiers in microbiology · 2022
    Article
  8. Chlamydia-induced curvature of the host-cell plasma membrane is required for infection.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  9. EnteropathogenicInternational journal of molecular sciences · 2020
    Article
  10. EnterohemorrhagicFrontiers in cell and developmental biology · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Stinging Tight Junctions With WASPs.Cellular and molecular gastroenterology and hepatology · 2018
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rocio TapiaDepartment of Medicine and Division of Gastroenterology and Nutrition, Loyola University Chicago, Chicago, IL, USA.
Sarah E KralicekDepartment of Medicine and Division of Gastroenterology and Nutrition, Loyola University Chicago, Chicago, IL, USA.
Gail A HechtDepartment of Medicine and Division of Gastroenterology and Nutrition, Loyola University Chicago, Chicago, IL, USA.
Loyola University Chicago · USEdward Hines, Jr. VA Hospital · US

Funding

Mechanisms of Enteropathogenic E. coli Effects on Polarity and Tight JunctionsR01DK097043 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HECHT, GAIL A · 2012 to 2016
$1.6M
Mechanisms of Cytoskeletal Regulation of Tight Junction Homeostasis and RepairI01BX002687 · VA · EDWARD HINES JR VA HOSPITAL · PI HECHT, GAIL A · 2016 to 2019
–
BLRD VA I01 BX002687NIDDK NIH HHS R01 DK097043
6 · The paper itself

Abstract

Enteropathogenic Escherichia coli (EPEC) uses a type III secretion system to inject effector proteins into host intestinal epithelial cells causing diarrhoea. EPEC infection redistributes basolateral proteins β1-integrin and Na

Indexed as

AnimalsCarrier ProteinsCell LineCell MembraneCell PolarityChloride-Bicarbonate AntiportersDiarrheaDogsDynaminsEndocytosisEnteropathogenic Escherichia coliEpithelial CellsEscherichia coli InfectionsEscherichia coli ProteinsHumansIntestinal MucosaCarrier ProteinsChloride-Bicarbonate AntiportersCRB3 protein, humanDynaminsEscherichia coli ProteinsEspFU protein, E coliIntracellular Signaling Peptides and ProteinsMap protein, E coliMembrane GlycoproteinsMembrane ProteinsMembrane Transport ProteinsMPP5 protein, humanNucleoside-Phosphate KinaseSLC26A3 protein, humanSNX9 protein, humanSodium-Potassium-Exchanging ATPaseSorting NexinsSulfate TransportersType III Secretion SystemsCrumbs3enteropathogenic Escherichia colipolaritytight junctions

Identifiers

PMID28618099
PMCPMC5645036
OpenAlexW2626054431

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.