Evidence map›Paper›PMID 28617941›Full record

ArticleClinical and experimental immunology2017

Association of immunoglobulin G4 and free light chain with idiopathic pleural effusion.

Y Murata, K Aoe, Y Mimura-Kimura, T Murakami, K Oishi, T Matsumoto, H Ueoka, K Matsunaga, M Yano, Y Mimura

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pleural effusion related to IgG4.Current opinion in pulmonary medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Y MurataThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
K AoeThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
Y Mimura-KimuraThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.ORCID 0000-0002-9500-9790
T MurakamiThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
K OishiThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
T MatsumotoThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
H UeokaThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
K MatsunagaThe Department of Respiratory Medicine and Infectious Disease, Yamaguchi University Graduate School of Medicine, Ube, Japan.
M YanoDivision of Cardiology, The Department of Medicine and Clinical Science, Ube, Japan.
Y MimuraThe Department of Clinical Research, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.ORCID 0000-0002-2979-7311
National Sanyo Hospital · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cause of pleural effusion remains uncertain in approximately 15% of patients despite exhaustive evaluation. As recently described immunoglobulin (Ig)G4-related disease is a fibroinflammatory disorder that can affect various organs, including the lungs, we investigate whether idiopathic pleural effusion includes IgG4-associated etiology. Between 2000 and 2012, we collected 830 pleural fluid samples and reviewed 35 patients with pleural effusions undiagnosed after pleural biopsy at Yamaguchi-Ube Medical Center. Importantly, IgG4 immunostaining revealed infiltration of IgG4-positive plasma cells in the pleura of 12 patients (34%, IgG4

Indexed as

AdultAgedCell MovementFemaleFibrosisFollow-Up StudiesHumansImmunoglobulin GImmunoglobulin Heavy ChainsImmunoglobulin Light ChainsImmunohistochemistryInflammationJapanLungMaleMiddle AgedImmunoglobulin GImmunoglobulin Heavy ChainsImmunoglobulin Light Chainsfibrinous pleuritisfree light chainIgG4-related diseasepleural effusion

Identifiers

PMID28617941
PMCPMC5588780
OpenAlexW2760906553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.