Evidence map›Paper›PMID 28617768›Full record

ArticleMMWR. Morbidity and mortality weekly report2017

Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease - United States.

Natalie S Marzec, Christina Nelson, Paul Ravi Waldron, Brian G Blackburn, Syed Hosain, Tara Greenhow, Gary M Green, Catherine Lomen-Hoerth, Marjorie Golden, Paul S Mead

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Lyme Neuroborreliosis.Deutsches Arzteblatt international · 2018
    Pooled it
  3. Review
  4. Lyme borreliosis.Nature reviews. Disease primers · 2026
    Review
  5. Article
  6. Review
  7. Current and emerging approaches for eliminatingFrontiers in microbiology · 2024
    Review
  8. Review
  9. Persistent Symptoms After Treatment of Lyme Disease.Infectious disease clinics of North America · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. Peripherally Inserted Central Catheter-AssociatedOpen forum infectious diseases · 2021
    Article
  14. Review
  15. A case ofInfectious disease reports · 2019
    Article
  16. Article
  17. Article
  18. Énoncé de position de l'AMMI Canada sur le diagnostic de la maladie de Lyme et le traitement des personnes ayant des symptômes persistants attribués à cette maladie.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2019
    Article
  19. AMMI Canada position statement on the diagnosis and treatment of people with persistent symptoms that have been attributed to Lyme disease.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Natalie S Marzec
Christina Nelson
Paul Ravi Waldron
Brian G Blackburn
Syed Hosain
Tara Greenhow
Gary M Green
Catherine Lomen-Hoerth
Marjorie Golden
Paul S Mead

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term "chronic Lyme disease" is used by some health care providers as a diagnosis for various constitutional, musculoskeletal, and neuropsychiatric symptoms (1,2). Patients with a diagnosis of chronic Lyme disease have been provided a wide range of medications as treatment, including long courses of intravenous (IV) antibiotics (3,4). Studies have not shown that such treatments lead to substantial long-term improvement for patients, and they can be harmful (1,5). This report describes cases of septic shock, osteomyelitis, Clostridium difficile colitis, and paraspinal abscess resulting from treatments for chronic Lyme disease. Patients, clinicians, and public health practitioners should be aware that treatments for chronic Lyme disease can carry serious risks.

Indexed as

Cross InfectionSeverity of Illness IndexAdolescentAdultBacterial InfectionsChronic DiseaseFatal OutcomeFemaleHumansLyme DiseaseMiddle AgedUnited States

Identifiers

PMID28617768
PMCPMC5657841
OpenAlexW2625012672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.