ArticleChemical communications (Cambridge, England)2017
Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy.
Article in Chemical communications (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 57 citations in OpenAlex.
- Homogeneous Antibody-DNA Conjugates Using Unmodified Oligonucleotides and Photo-Cross-Linkable Protein G-HUH Endonuclease Fusion Proteins.Bioconjugate chemistry · 2026Article
- DNA Origami Barcodes for Immunostaining.ACS applied materials & interfaces · 2025Article
- Folding and Functionalizing DNA Origami: A Versatile Approach Using a Reactive Polyamine.Journal of the American Chemical Society · 2025Article
- Cargo quantification of functionalized DNA origami for therapeutic application.bioRxiv : the preprint server for biology · 2024Article
- Minimizing Structural Heterogeneity in DNA Self-Assembled Dye Templating via DNA Origami-Tuned Conformations.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- Programmable multispecific DNA-origami-based T-cell engagers.Nature nanotechnology · 2023Article
- Article
- Functionalizing DNA origami to investigate and interact with biological systems.Nature reviews. Materials · 2023Article
- Structural characterization of humanFrontiers in oncology · 2023Article
- Synthesis of Protein-Oligonucleotide Conjugates.Biomolecules · 2022Review
- Single molecule DNA origami nanoarrays with controlled protein orientation.Biophysics reviews · 2022Article
- Optically Responsive Protein Coating of DNA Origami for Triggered Antigen Targeting.ACS applied materials & interfaces · 2022Article
- Functionalizing DNA nanostructures for therapeutic applications.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021Review
- Affinity-Based Methods for Site-Specific Conjugation of Antibodies.Bioconjugate chemistry · 2021Review
- Determinants of Ligand-Functionalized DNA Nanostructure-Cell Interactions.Journal of the American Chemical Society · 2021Article
- Non-specific interactions of antibody-oligonucleotide conjugates with living cells.Scientific reports · 2021Article
- Nuclease resistance of DNA nanostructures.Nature reviews. Chemistry · 2021Review
- Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers.Nucleic acids research · 2020Article
- Bioluminescent Antibodies through Photoconjugation of Protein G-Luciferase Fusion Proteins.Bioconjugate chemistry · 2020Article
- Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome.Nature catalysis · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A photocrosslinkable protein G variant was used as an adapter protein to covalently and site-specifically conjugate an antibody and an Fc-fusion protein to an oligonucleotide. This modular approach enables straightforward decoration of DNA nanostructures with complex native proteins while retaining their innate binding affinity, allowing precise control over the nanoscale spatial organization of such proteins for in vitro and in vivo biomedical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.