ArticleBritish journal of pharmacology2018
Loops D, E and G in the Drosophila Dα1 subunit contribute to high neonicotinoid sensitivity of Dα1-chicken β2 nicotinic acetylcholine receptor.
Article in British journal of pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 26 citations in OpenAlex.
- Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquitoOpen biology · 2024Article
- (-)-Adaline from theMolecules (Basel, Switzerland) · 2022Article
- Slo2/KThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Neuronal octopamine signaling regulates mating-induced germline stem cell increase in femaleeLife · 2020Article
- Loops D, E and G in the Drosophila Dα1 subunit contribute to high neonicotinoid sensitivity of Dα1-chicken β2 nicotinic acetylcholine receptor.British journal of pharmacology · 2018Article
- Nicotinic acetylcholine receptors.British journal of pharmacology · 2018Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeNeonicotinoid insecticides interact with the orthosteric site formed at subunit interfaces of insect nicotinic ACh (nACh) receptors. However, their interactions with the orthosteric sites at α-non α and α-α subunit interfaces remain poorly understood. The aim of this study was to elucidate the mechanism of neonicotinoid actions using the Drosophila Dα1-chicken β2 hybrid nACh receptor. EXPERIMENTAL APPROACH: Computer models of the (Dα1) KEY
resultsThe (Dα1) CONCLUSIONS AND IMPLICATIONS: These findings suggest that a triangle of residues from loops D, E and G contribute to the selective actions of neonicotinoids on insect-vertebrate hybrid nACh receptors. LINKED ARTICLES: This article is part of a themed section on Nicotinic Acetylcholine Receptors. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.11/issuetoc.
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Registered trials
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