SynthesisClinical oral investigations2018
Systematic review of oral manifestations related to hyperparathyroidism.
Synthesis in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 62 citations in OpenAlex.
- Tooth mobility revealing a brown tumor associated with normocalcemic hyperparathyroidism: case report and literature review.BMC oral health · 2026Review
- Osteitis fibrosa cystica recovery following parathyroidectomy for primary hyperparathyroidism: a case series and review of literature.JBMR plus · 2025Review
- Evaluation of 3-year changes in panoramic radiomorphometric indices and fractal dimension values in primary hyperparathyroidism patients.European journal of medical research · 2025Article
- Control of alveolar bone development, homeostasis, and socket healing by salt-inducible kinases.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025Article
- Influence of normocalcemic primary hyperparathyroidism in bone density alterations of the jaws in patients with periodontitis.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Article
- Craniofacial disorders and dysplasias: Molecular, clinical, and management perspectives.Bone reports · 2024Review
- Rare Case of a Peripheral Giant Cell Granuloma of the Jaw as First Manifestation of Primary Hyperparathyroidism.Diagnostics (Basel, Switzerland) · 2022Article
- Torus Mandibularis in Patients Receiving Hemodialysis.International journal of environmental research and public health · 2021Observational
- A patient with multiple brown tumors due to secondary hyperparathyroidism: A case report.Radiology case reports · 2021Article
- Imaging technologies in the differential diagnosis and follow-up of brown tumor in primary hyperparathyroidism: Case report and review of the literature.Bone reports · 2021Article
- Increased risk for tooth extraction in primary hyperparathyroidism and hypercalcemia: a population study.Clinical oral investigations · 2020Article
- Surgical osteoplasty and soft tissue excision as treatment for facial deformities in patients with renal osteodystrophy: three case reports.Oral and maxillofacial surgery · 2020Article
- Parathyroidectomy Resolves Tooth Discoloration: A New Presenting Sign of Hyperparathyroidism?Case reports in dentistry · 2020Article
- Brown tumor complicating end-stage kidney disease.Clinical nephrology. Case studies · 2020Article
- Rare brown tumour of the mandible secondary to tertiary hyperparathyroidism in a renal transplant recipient.BMJ case reports · 2019Article
- Uremic leontiasis ossea due to secondary hyperparathyroidism complicated by vitamin C deficiency in a non-adherent chronic hemodialysis patient: A case report.Clinical nephrology. Case studies · 2019Article
- Brown tumor of multiple facial bones associated with primary hyperparathyroidism: A clinical case report.Medicine · 2018Article
- Survey of Torus Palatinus in Patients with End-Stage Renal Disease Undergoing Hemodialysis.BioMed research international · 2018Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe sought to identify oral symptoms found in hyperparathyroidism and compare their rate of occurrence, as well as potential variations in sequelae between primary, secondary, and tertiary hyperparathyroidism. MATERIALS AND
methodsDatabase searches were performed through EMBASE and PubMed, with a continual handsearch for relevant articles. PRISMA guidelines were followed.
resultsTwo hundred five articles including 245 patients were analyzed with data extraction. The average age was 34.02 years old (age range 1-83), with 91 male and 154 female patients (1:1.7 M/F ratio). Patients presented with symptoms including facial asymmetry or swelling (167/214 cases; 78.0%), oral pain (30/214; 14.0%), systemic symptoms (25/214; 11.7%), referrals or incidental findings (16/214; 7.5%), and neuropathy (6/214; 2.8%) independently and in combination together. Bony pathology occurred most often in the mandible (100/245 cases; 40.8%), while 72 cases were in the maxilla (29.4%) and 73 cases in both jaw bones (29.8%).
conclusionsOur data collection identifies a wide variation in the presentation of hyperparathyroidism. In order to be more certain of oral maladies from hyperparathyroidism, studies with large patient populations need to be conducted at healthcare centers to clarify the oral outcomes of hyperparathyroidism. CLINICAL RELEVANCE: What was thought to be a characteristic finding of HPT, mandibular radiolucency occurred in only a minor portion of cases. Furthermore, the pathognomonic sign of HPT on radiograph, loss of lamina dura, was only the third most common presentation. Bone pathology was most commonly reported in literature, but should not be assumed the only oral sequelae of hyperparathyroidism.
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