Evidence map›Paper›PMID 28616529›Full record

ArticleInternational journal of cardiology. Heart & vasculature2016

Intima-media thickness of the descending aorta in patients with bicuspid aortic valve.

Johan Petrini, Mohamed Yousry, Per Eriksson, Hanna M Björk, Anette Rickenlund, Anders Franco-Cereceda, Kenneth Caidahl, Maria J Eriksson

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Pathobiological Mechanisms of Endothelial Dysfunction Induced byInternational journal of medical sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Johan PetriniDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Mohamed YousryDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Per ErikssonAtherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Hanna M BjörkAtherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Anette RickenlundDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Anders Franco-CerecedaDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Kenneth CaidahlDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Maria J ErikssonDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEStockholm South General Hospital · SESuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA bicuspid aortic valve (BAV) is associated with accelerated aortic valve disease (AVD) and abnormalities in aortic elasticity. We investigated the intima-media thickness of the descending aorta (AoIMT) in patients with AVD with or without an ascending aortic aneurysm (AscAA), in relation to BAV versus tricuspid aortic valve (TAV) phenotype, type of valve disease, cardiovascular risk factors, and single-nucleotide polymorphisms (SNPs) with a known association with carotid IMT. METHODS AND

results368 patients (210 with BAV, 158 with TAV,); mean age 64 ± 13 years) were examined using transesophageal echocardiography (TEE) before valvular and/or aortic surgery. No patient had a coronary disease (CAD). The AoIMT was measured on short-axis TEE images of the descending aorta using a semi-automated edge-detection technique. AoIMT was univariately (

conclusionsIntima-media thickness of the descending aorta is not affected by aortic valve morphology (BAV/TAV); age is the main determinant of AoIMT. Genetic markers (SNPs) known to influence IMT in the carotid artery seem to correlate to IMT in the descending aorta only in patients with TAV.

Indexed as

Aortic regurgitationAortic stenosisBicuspid aortic valveDescending aortaGeneticsIntima-media thickness

Identifiers

PMID28616529
PMCPMC5441363
OpenAlexW2334910660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.