Evidence map›Paper›PMID 28616468›Full record

ArticleOne health (Amsterdam, Netherlands)2015

Absence of MERS-CoV antibodies in feral camels in Australia: Implications for the pathogen's origin and spread.

Gary Crameri, Peter A Durr, Jennifer Barr, Meng Yu, Kerryne Graham, Owen J Williams, Ghazi Kayali, David Smith, Malik Peiris, John S Mackenzie and 1 more

Open access · goldAbstract read
In one paragraph

Article in One health (Amsterdam, Netherlands), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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  6. MERS-CoV: epidemiology, molecular dynamics, therapeutics, and future challenges.Annals of clinical microbiology and antimicrobials · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 4 countries.

Gary CrameriCSIRO Australian Animal Health Laboratory, Geelong, Australia.
Peter A DurrCSIRO Australian Animal Health Laboratory, Geelong, Australia.
Jennifer BarrCSIRO Australian Animal Health Laboratory, Geelong, Australia.
Meng YuCSIRO Australian Animal Health Laboratory, Geelong, Australia.
Kerryne GrahamCSIRO Australian Animal Health Laboratory, Geelong, Australia.
Owen J WilliamsEarlville Veterinary Surgery, Cairns, Australia.
Ghazi KayaliDivision of Environmental Research, National Research Centre, Giza, Egypt.
David SmithSchool of Pathology and Laboratory Medicine, University of WA, Nedlands, Australia.
Malik PeirisSchool of Public Health, the University of Hong Kong, Hong Kong, China.
John S MackenzieFaculty of Health Sciences, Curtin University, Perth, WA, Australia.
Lin-Fa WangCSIRO Australian Animal Health Laboratory, Geelong, Australia.
Australian Centre for Disease Preparedness · AUCommonwealth Scientific and Industrial Research Organisation · AUCurtin University · AUNational Research Centre · EGRacing Victoria · AUUniversity of Hong Kong · HKUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) infections continue to be a serious emerging disease problem internationally with well over 1000 cases and a major outbreak outside of the Middle East region. While the hypothesis that dromedary camels are the likely major source of MERS-CoV infection in humans is gaining acceptance, conjecture continues over the original natural reservoir host(s) and specifically the role of bats in the emergence of the virus. Dromedary camels were imported to Australia, principally between 1880 and 1907 and have since become a large feral population inhabiting extensive parts of the continent. Here we report that during a focussed surveillance study, no serological evidence was found for the presence of MERS-CoV in the camels in the Australian population. This finding presents various hypotheses about the timing of the emergence and spread of MERS-CoV throughout populations of camels in Africa and Asia, which can be partially resolved by testing sera from camels from the original source region, which we have inferred was mainly northwestern Pakistan. In addition, we identify bat species which overlap (or neighbour) the range of the Australian camel population with a higher likelihood of carrying CoVs of the same lineage as MERS-CoV. Both of these proposed follow-on studies are examples of "proactive surveillance", a concept that has particular relevance to a One Health approach to emerging zoonotic diseases with a complex epidemiology and aetiology.

Indexed as

BatsCamelsCoronavirus (CoV)Middle East respiratory syndrome (MERS)Serological surveillanceSevere acute respiratory syndrome (SARS)

Identifiers

PMID28616468
PMCPMC5441328
OpenAlexW1941852407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.