ReviewRegeneration (Oxford, England)2017
Regulation of dorso-ventral polarity by the nerve cord during annelid regeneration: A review of experimental evidence.
Review in Regeneration (Oxford, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Nerves and availability of mesodermal cells are essential for the function of the segment addition zone (SAZ) during segment regeneration in polychaete annelids.Development genes and evolution · 2024Review
- The sea spiderProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Neural regulation of body polarities in nereid worm regeneration.FASEB bioAdvances · 2022Article
- Studying Annelida Regeneration Using Platynereis dumerilii.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Regeneration in the Segmented AnnelidGenes · 2021Review
- Comparative Aspects of Annelid Regeneration: Towards Understanding the Mechanisms of Regeneration.Genes · 2021Review
- It Cuts Both Ways: An Annelid Model System for the Study of Regeneration in the Laboratory and in the Classroom.Frontiers in cell and developmental biology · 2021Review
- Article
- A Revised Spiralian Homeobox Gene Classification Incorporating New Polychaete Transcriptomes Reveals a Diverse TALE Class and a Divergent Hox Gene.Genome biology and evolution · 2018Article
- Regeneration mechanisms in Syllidae (Annelida).Regeneration (Oxford, England) · 2018Review
- Regulation of dorso-ventral polarity by the nerve cord during annelid regeneration: A review of experimental evidence.Regeneration (Oxford, England) · 2017Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An important goal for understanding regeneration is determining how polarity is conferred to the regenerate. Here we review findings in two groups of polychaete annelids that implicate the ventral nerve cord in assigning dorso-ventral polarity, and specifically ventral identity, to the regenerate. In nereids, surgical manipulations indicate that parapodia develop where dorsal and ventral body wall territories contact. Without a nerve cord at the wound site, the regenerate differentiates no evident polarity (with no parapodia) and only dorsal identity, while with two nerve cords the regenerate develops a twinned dorso-ventral axis (with four parapodia per segment instead of the normal two). In sabellids, a striking natural dorso-ventral inversion in parapodial morphology occurs along the body axis and this inversion is morphologically correlated with the position of the nerve cord. Parapodial inversion also occurs in segments in which the nerve cord has been removed, even without any segment amputation. Together, these data strongly support a role for the nerve cord in annelid dorso-ventral pattern regulation, with the nerve cord conferring ventral identity.
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