Evidence map›Paper›PMID 28616179›Full record

ArticleEcology and evolution2017

Prediction of harmful variants on mitochondrial genes: Test of habitat-dependent and demographic effects in a euryhaline fish.

Anti Vasemägi, Janne Sulku, Matthieu Bruneaux, Olaf Thalmann, Hannu Mäkinen, Mikhail Ozerov

Abstract read
In one paragraph

Article in Ecology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anti VasemägiDepartment of Biology University of Turku Turku Finland.ORCID 0000-0002-2184-5534
Janne SulkuDepartment of Biology University of Turku Turku Finland.
Matthieu BruneauxDepartment of Biology University of Turku Turku Finland.
Olaf ThalmannDepartment of Biology University of Turku Turku Finland.
Hannu MäkinenDepartment of Biology University of Turku Turku Finland.
Mikhail OzerovDepartment of Biology University of Turku Turku Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both effective population size and life history may influence the efficacy of purifying selection, but it remains unclear if the environment affects the accumulation of weakly deleterious nonsynonymous polymorphisms. We hypothesize that the reduced energetic cost of osmoregulation in brackish water habitat may cause relaxation of selective constraints at mitochondrial oxidative phosphorylation (OXPHOS) genes. To test this hypothesis, we analyzed 57 complete mitochondrial genomes of

Indexed as

adaptationgenetic loadmtDNAnearly neutral theory of molecular evolutionselective constraint

Identifiers

PMID28616179
PMCPMC5468147

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.