Evidence map›Paper›PMID 28616085›Full record

ReviewJournal of medicine and life

Helicobacter pylori infection: old and new.

S Diaconu, A Predescu, A Moldoveanu, C S Pop, C Fierbințeanu-Braticevici

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05787262 (Clinical Utility of Upper Endoscopy in Diagnosis of Helicobacter Pylori Infection), which is not on this map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05787262 naunknown statusnot on this map

Clinical Utility of Upper Endoscopy in Diagnosis of Helicobacter Pylori Infection

TypeinterventionalSponsorSohag UniversityRan2023 to 2024Enrolled345ConditionsHelicobacter Pylori InfectionArmsupper endoscopy
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 123 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Update on the pathogenesis and clinical management ofWorld journal of gastrointestinal pathophysiology · 2025
    Review
  5. Systemic Impact ofJGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  6. Preventive medicine reports · 2025
    Article
  7. Effect ofImmunotherapy · 2025
    Review
  8. Machine Learning-Based Prediction of Helicobacter pylori Infection Study in Adults.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  9. Article
  10. The effect of three urease inhibitors onFrontiers in microbiology · 2024
    Article
  11. Article
  12. Role of non-World journal of gastroenterology · 2023
    Review
  13. Study of the Effect of Baicalin fromInternational journal of molecular sciences · 2023
    Article
  14. Review
  15. Article
  16. Gastric Mucosa-associated Lymphoid Tissue Lymphoma Mimicking Signet Ring Cell Carcinoma.The Korean journal of helicobacter and upper gastrointestinal research · 2023
    Article
  17. Article
  18. Article
  19. Global Trend on Machine Learning inGlobal health, epidemiology and genomics · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

S DiaconuDepartment of Internal Medicine II and Gastroenterology, University Emergency Hospital, Bucharest, Romania.
A PredescuDepartment of Internal Medicine II and Gastroenterology, University Emergency Hospital, Bucharest, Romania.
A MoldoveanuDepartment of Internal Medicine II and Gastroenterology, University Emergency Hospital, Bucharest, Romania.
C S PopDepartment of Internal Medicine II and Gastroenterology, University Emergency Hospital, Bucharest, Romania.
C Fierbințeanu-BraticeviciDepartment of Internal Medicine II and Gastroenterology, University Emergency Hospital, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori is a spiral-shaped bacterium that grows in the digestive tract and may be present in more than half of the world's population. The clinical features of Helicobacter pylori range from asymptomatic gastritis to gastrointestinal malignancy. Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade B-cell marginal zone lymphoma and Helicobacter pylori has been detected in more than 75% of the patients with MALT lymphoma. Many tests for the detection of Helicobacter pylori are available, including antibody tests, urea breath tests, stool antigen tests and endoscopic biopsies. The eradication of Helicobacter pylori usually prevents the return of ulcers and ulcer complications even after appropriate medications such as PPIs are stopped. The eradication of Helicobacter pylori is important in the treatment of the rare condition of the stomach known as MALT lymphoma. The treatment of Helicobacter pylori to prevent stomach cancer is controversial. Confirmation of eradication is recommended in associated ulcers, persistent dyspepsia despite a test-and-treat approach, MALT lymphoma, and previous treatment for early-stage gastric cancer. The urea breath test and stool antigen test can be used to confirm the eradication and should be performed at least 4 weeks after the completion of therapy. Several diseases have been reported to be associated with Helicobacter pylori infection, including hematologic diseases, such as ITP, idiopathic iron deficiency anemia and vitamin B12 deficiency. There is a positive trend in the association between Helicobacter pylori infection and neurodegenerative disorders and new data showed a reduced risk of death due to stroke and lung cancer but an increased risk of preeclampsia in infected women, which requires further investigations.

Indexed as

Disease ProgressionHelicobacter InfectionsHelicobacter pyloriHumansTreatment Failuregastric carcinomagastritisHelicobacter pyloriproton pump inhibitorulcer

Identifiers

PMID28616085
PMCPMC5467250
OpenAlexW2884301716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.