Evidence map›Paper›PMID 28616073›Full record

ArticleBiotechnology for biofuels2017

The transcription factor PDR-1 is a multi-functional regulator and key component of pectin deconstruction and catabolism in

Nils Thieme, Vincent W Wu, Axel Dietschmann, Asaf A Salamov, Mei Wang, Jenifer Johnson, Vasanth R Singan, Igor V Grigoriev, N Louise Glass, Chris R Somerville and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
7.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. The genome-scale sugar metabolic model fromCurrent research in microbial sciences · 2026
    Article
  2. Identification and Classification of Fungal GPCR Gene Families.Journal of fungi (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Regulation of nutrient utilization in filamentous fungi.Applied microbiology and biotechnology · 2023
    Review
  5. Article
  6. Article
  7. The F-box protein geneProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Review
  9. Article
  10. The regulatory and transcriptional landscape associated with carbon utilization in a filamentous fungus.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Nils ThiemeHFM, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.
Vincent W WuDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA USA.
Axel DietschmannHFM, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.
Asaf A SalamovUS Department of Energy Joint Genome Institute (JGI), Walnut Creek, CA USA.
Mei WangUS Department of Energy Joint Genome Institute (JGI), Walnut Creek, CA USA.
Jenifer JohnsonUS Department of Energy Joint Genome Institute (JGI), Walnut Creek, CA USA.
Vasanth R SinganUS Department of Energy Joint Genome Institute (JGI), Walnut Creek, CA USA.
Igor V GrigorievDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA USA.
N Louise GlassDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA USA.ORCID 0000-0002-4844-2890
Chris R SomervilleDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA USA.ORCID 0000-0003-4647-0094
J Philipp BenzHFM, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.ORCID 0000-0001-5361-4514
Joint Genome Institute · USEnergy Biosciences Institute · USTechnical University of Munich · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DELawrence Berkeley National Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPectin is an abundant component in many fruit and vegetable wastes and could therefore be an excellent resource for biorefinery, but is currently underutilized. Fungal pectinases already play a crucial role for industrial purposes, such as for foodstuff processing. However, the regulation of pectinase gene expression is still poorly understood. For an optimal utilization of plant biomass for biorefinery and biofuel production, a detailed analysis of the underlying regulatory mechanisms is warranted. In this study, we applied the genetic resources of the filamentous ascomycete species

resultsThe pectin degradation regulator-1 (PDR-1) was identified through a transcription factor mutant screen in

conclusionsPDR-1 is highly conserved in filamentous ascomycete fungi and is present in many pathogenic and industrially important fungi. Our data demonstrate that the function of PDR-1 in

Indexed as

Biorefineryd-galacturonic acid catabolismGene regulationl-rhamnose catabolismNeurospora crassaPectin degradationZn2Cys6 transcription factor

Identifiers

PMID28616073
PMCPMC5469009
OpenAlexW2625295830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.