Evidence map›Paper›PMID 28615976›Full record

ReviewMedical devices (Auckland, N.Z.)2017

Clinical utility of neurostimulation devices in the treatment of overactive bladder: current perspectives.

Dick Aw Janssen, Frank Mj Martens, Liesbeth L de Wall, Hendrikje Mk van Breda, John Pfa Heesakkers

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Medical devices (Auckland, N.Z.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04120545 nacompletednot on this mapstarted 2019, after this paper: background citation

Effectiveness of Microcurrents Therapy in Overactive Bladder : Controlled and Randomized Triple Blind Clinical Trial

TypeinterventionalSponsorUniversity of Las Palmas de Gran CanariaRan2019 to 2021Enrolled56ConditionsOveractive Bladder, Urinary IncontinenceArmsMicrocurrents, Placebo Microcurrents
NCT04364438 naunknown statusnot on this mapstarted 2020, after this paper: background citation

A Randomized Controlled Trial on Effectiveness of Electric Muscle Stimulation (EMS) and Transcutaneous Electric Nerve Stimulation (TENS) in Patients With Overactive Bladder

TypeinterventionalSponsorIsra UniversityRan2020 to 2021Enrolled315ConditionsOveractive BladderArmsElectric Muscle Stimulation, Transcutaneous Electric Nerve Stimulation
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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  13. Sharpened and Mechanically Durable Carbon Fiber Electrode Arrays for Neural Recording.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Dick Aw JanssenDepartment of Urology, Radboud University Nijmegen Medical Center, Nijmegen.
Frank Mj MartensDepartment of Urology, Radboud University Nijmegen Medical Center, Nijmegen.
Liesbeth L de WallDepartment of Urology, Radboud University Nijmegen Medical Center, Nijmegen.
Hendrikje Mk van BredaDepartment of Urology, University Medical Center Utrecht, Utrecht, the Netherlands.
John Pfa HeesakkersDepartment of Urology, Radboud University Nijmegen Medical Center, Nijmegen.
Radboud University Nijmegen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis review describes the evidence from established and experimental therapies that use electrical nerve stimulation to treat lower urinary tract dysfunction.

methodsClinical studies on established treatments such as percutaneous posterior tibial nerve stimulation (P-PTNS), transcutaneous electrical nerve stimulation (TENS), sacral nerve stimulation (SNS) and sacral anterior root stimulation (SARS) are evaluated. In addition, clinical evidence from experimental therapies such as dorsal genital nerve (DGN) stimulation, pudendal nerve stimulation, magnetic nerve stimulation and ankle implants for tibial nerve stimulation are evaluated.

resultsSNS and P-PTNS have been investigated with high-quality studies that have shown proven efficacy for the treatment for overactive bladder (OAB). SARS has proven evidence-based efficacy in spinal cord patients and increases the quality of life. TENS seems inferior to other OAB treatments such as SNS and P-PTNS but is noninvasive and applicable for ambulant therapy. Results from studies on experimental therapies such as pudendal nerve stimulation seem promising but need larger study cohorts to prove efficacy.

conclusionNeurostimulation therapies have proven efficacy for bladder dysfunction in patients who are refractory to other therapies. SIGNIFICANCE: Refinement of neurostimulation therapies is possible. The aim should be to make the treatments less invasive, more durable and more effective for the treatment of lower urinary tract dysfunction.

Indexed as

implantneuromodulationoveractive bladder syndromePTNSsacral anterior root stimulationsacral nerve stimulation

Identifiers

PMID28615976
PMCPMC5460621
OpenAlexW2620863204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.