ArticleIndian journal of psychological medicine
Neurocognitive Impairments in Unaffected First-degree Relatives of Schizophrenia.
Article in Indian journal of psychological medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Assessment of Social Functioning in Patients With Schizophrenia and Their First-Degree Relatives.Journal of clinical medicine research · 2026Article
- Clustering of cognitive subtypes in schizophrenia patients and their siblings: relationship with regional brain volumes.Schizophrenia (Heidelberg, Germany) · 2022Article
- Subjective Cognitive Complaints in Unaffected First-Degree Relatives of Schizophrenia Patients: Relation to Cognitive Performance, Psychotic Experiences, and Social Functioning.Indian journal of psychological medicine · 2022Article
- The Limitations of Quasi-Experimental Studies, and Methods for Data Analysis When a Quasi-Experimental Research Design Is Unavoidable.Indian journal of psychological medicine · 2021Article
- Metabolite Alterations in Adults With Schizophrenia, First Degree Relatives, and Healthy Controls: A Multi-Region 7T MRS Study.Frontiers in psychiatry · 2021Article
- Discovery biology of neuropsychiatric syndromes (DBNS): a center for integrating clinical medicine and basic science.BMC psychiatry · 2018Article
- Neurocognitive Profile in Indian Individuals Genetically at Risk of Schizophrenia.Indian journal of psychological medicineArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeurocognitive impairments of attention and executive functioning are trait abnormalities in schizophrenia, and these are considered to be endophenotypes. These deficits have been convincingly linked to prefrontal cortical functioning. In this study, we examined the cognitive performance in the domains of attention and executive functioning among first-degree relatives of Indian people with schizophrenia (high-risk [HR] patients) compared to healthy controls (HC). MATERIALS AND
methodsSiblings of patients with DSM-IV schizophrenia, HR patients (
resultsHR patients had significantly deficient performance in attention and executive function tasks (DST-forward [
conclusionsThis study replicates the findings that neurocognitive deficits involving executive function task performance, attention, and working memory, which are considered as principal features in patients with schizophrenia, are also significantly present in the first-degree relatives of patients. Thus, these neurocognitive parameters can be considered as potential endophenotypes in schizophrenia.
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