Evidence map›Paper›PMID 28615505›Full record

ArticleProceedings. Biological sciences2017

Topological features of a gene co-expression network predict patterns of natural diversity in environmental response.

David L Des Marais, Rafael F Guerrero, Jesse R Lasky, Samuel V Scarpino

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Impacts of limits to adaptation on population and community persistence in a changing environment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Co-expression Networks in Predicting Transcriptional Gene Regulation.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Combining population genomics and fitness QTLs to identify the genetics of local adaptation inProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

David L Des MaraisArnold Arboretum and Department of Organismic and Evolutionary Biology, Harvard University, 1300 Centre Street, Boston, MA 20131, USA desmarais@fas.harvard.edu.ORCID http://orcid.org/0000-0002-6772-6987
Rafael F GuerreroDepartment of Biology, Indiana University, Jordan Hall 142, Bloomington, IN 47405, USA.ORCID http://orcid.org/0000-0002-8451-3609
Jesse R LaskyDepartment of Biology, Pennsylvania State University, 408 Life Sciences Building, University Park, PA 16802, USA.ORCID http://orcid.org/0000-0001-7688-5296
Samuel V ScarpinoDepartment of Mathematics and Statistics and Vermont Complex Systems Center, University of Vermont, 210 Colchester Avenue, Burlington, VT 05405, USA samuel.v.scarpino@uvm.edu.ORCID http://orcid.org/0000-0001-5716-2770
Harvard University · USIndiana University Bloomington · USPennsylvania State University · USUniversity of Vermont · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular interactions affect the evolution of complex traits. For instance, adaptation may be constrained by pleiotropic or epistatic effects, both of which can be reflected in the structure of molecular interaction networks. To date, empirical studies investigating the role of molecular interactions in phenotypic evolution have been idiosyncratic, offering no clear patterns. Here, we investigated the network topology of genes putatively involved in local adaptation to two abiotic stressors-drought and cold-in

Indexed as

Cold TemperatureDroughtsGene Regulatory NetworksAdaptation, PhysiologicalArabidopsisGene Expression Regulation, Plantabiotic stressArabidopsis thalianacolddroughtgene by environment interactiongene regulatory network

Identifiers

PMID28615505
PMCPMC5474086
OpenAlexW2625820467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.