Evidence map›Paper›PMID 28615475›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Infantile Amnesia: A Critical Period of Learning to Learn and Remember.

Cristina M Alberini, Alessio Travaglia

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 206 citations in OpenAlex.

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  13. Developmental changes in brain-wide fear memory networks.Neurobiology of learning and memory · 2025
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cristina M AlberiniCenter for Neural Science, New York University, New York, New York 10003 ca60@nyu.edu.ORCID 0000-0001-7386-0018
Alessio TravagliaCenter for Neural Science, New York University, New York, New York 10003.
New York University · US

Funding

Gene Expression in Long-Term MemoryR01MH065635 · NIMH · NEW YORK UNIVERSITY · PI CRISTINA M ALBERINI · 2002 to 2026
$7.5M
Gene Expression in Long-Term MemoryR37MH065635 · NIMH · NEW YORK UNIVERSITY · PI ALBERINI, CRISTINA M · 2013 to 2022
$5.6M
Mechanism Underlying Memory StabilizationR01MH074736 · NIMH · NEW YORK UNIVERSITY · PI ALBERINI, CRISTINA M · 2007 to 2016
$5.0M
NIMH NIH HHS R01 MH065635NIMH NIH HHS R01 MH074736NIMH NIH HHS R37 MH065635
6 · The paper itself

Abstract

Infantile amnesia, the inability of adults to recollect early episodic memories, is associated with the rapid forgetting that occurs in childhood. It has been suggested that infantile amnesia is due to the underdevelopment of the infant brain, which would preclude memory consolidation, or to deficits in memory retrieval. Although early memories are inaccessible to adults, early-life events, such as neglect or aversive experiences, can greatly impact adult behavior and may predispose individuals to various psychopathologies. It remains unclear how a brain that rapidly forgets, or is not yet able to form long-term memories, can exert such a long-lasting and important influence. Here, with a particular focus on the hippocampal memory system, we review the literature and discuss new evidence obtained in rats that illuminates the paradox of infantile amnesia. We propose that infantile amnesia reflects a developmental critical period during which the learning system is learning how to learn and remember.

Indexed as

Critical Period, PsychologicalMemory, Long-TermMental RecallAgingAmnesiaAnimalsEvidence-Based MedicineHippocampusHumansInfantInfant, NewbornModels, NeurologicalNerve NetRats

Identifiers

PMID28615475
PMCPMC5473198
OpenAlexW2626690396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.