Evidence map›Paper›PMID 28615445›Full record

ReviewThe Journal of biological chemistry2017

Iron-sulfur cluster biogenesis and trafficking in mitochondria.

Joseph J Braymer, Roland Lill

Abstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 216 papers.

0numbers the graph read from it
0cells of the map it votes in
216citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

216 citing papers in PubMed.

  1. Article
  2. Ferroptosis in liver biology and diseases.Hepatology communications · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Regulation of mitochondrial iron homeostasis in tumor cells.Molecular medicine (Cambridge, Mass.) · 2026
    Review
  10. Unveiling Specificity, Redundancy, and Promiscuity of FiveInternational journal of molecular sciences · 2026
    Article
  11. Review
  12. Article
  13. Frontiers in cellular and infection microbiology · 2026
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

156 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph J BraymerInstitut für Zytobiologie und Zytopathologie, Philipps-Universität Marburg, Robert-Koch-Strasse 6, 35032 Marburg.
Roland LillInstitut für Zytobiologie und Zytopathologie, Philipps-Universität Marburg, Robert-Koch-Strasse 6, 35032 Marburg; LOEWE Zentrum für Synthetische Mikrobiologie SynMikro, Hans-Meerwein-Strasse, 35043 Marburg, Germany. Electronic address: lill@staff.uni-marburg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biogenesis of iron-sulfur (Fe/S) proteins in eukaryotes is a multistage, multicompartment process that is essential for a broad range of cellular functions, including genome maintenance, protein translation, energy conversion, and the antiviral response. Genetic and cell biological studies over almost 2 decades have revealed some 30 proteins involved in the synthesis of cellular [2Fe-2S] and [4Fe-4S] clusters and their incorporation into numerous apoproteins. Mechanistic aspects of Fe/S protein biogenesis continue to be elucidated by biochemical and ultrastructural investigations. Here, we review recent developments in the pursuit of constructing a comprehensive model of Fe/S protein assembly in the mitochondrion.

Indexed as

Gene Expression Regulation, EnzymologicModels, BiologicalModels, MolecularAcyl Carrier ProteinAdrenodoxinAnimalsApoenzymesFrataxinHumansIron-Binding ProteinsIron-Sulfur ProteinsMitochondriaMitochondrial ProteinsProtein ConformationProtein FoldingProtein MultimerizationAcyl Carrier ProteinAdrenodoxinApoenzymesFrataxinIron-Binding ProteinsIron-Sulfur ProteinsIsd11 protein, S cerevisiaeISU1 protein, S cerevisiaeMitochondrial ProteinsNFS1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSulfurtransferasesYAH1 protein, S cerevisiaeacyl carrier protein (ACP)chaperonecysteine desulfurasefatty acid metabolismferredoxinfrataxinglutaredoxinlipoic acidmetal biologymitochondrial disease

Identifiers

PMID28615445
PMCPMC5546016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.