Evidence map›Paper›PMID 28615224›Full record

ArticleCancer research2017

Risk of Second Malignancies in Solid Organ Transplant Recipients Who Develop Keratinocyte Cancers.

Rachel D Zamoiski, Elizabeth Yanik, Todd M Gibson, Elizabeth K Cahoon, Margaret M Madeleine, Charles F Lynch, Sally Gustafson, Marc T Goodman, Melissa Skeans, Ajay K Israni and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Interventions After First Post-Transplant Cutaneous Squamous Cell Carcinoma: A Proposed Decision Framework.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Review
  7. Lifetime Ambient UV Radiation Exposure and Risk of Basal Cell Carcinoma by Anatomic Site in a Nationwide U.S. Cohort, 1983-2005.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  8. Article
  9. Recurrent squamous cell carcinoma in a post cardiac transplant patient.International journal of surgery case reports · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Risk of lip cancer after solid organ transplantation in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Rachel D ZamoiskiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland.
Elizabeth YanikDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland.
Todd M GibsonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.
Elizabeth K CahoonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland.
Margaret M MadeleinePublic Health Science, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Charles F LynchDepartment of Epidemiology, University of Iowa, Iowa City, Iowa.
Sally GustafsonScientific Registry of Transplant Recipients, Minneapolis, Minnesota.
Marc T GoodmanCancer Prevention and Control Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Melissa SkeansScientific Registry of Transplant Recipients, Minneapolis, Minnesota.
Ajay K IsraniDepartment of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota.
Eric A EngelsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland.
Lindsay M MortonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland. mortonli@mail.nih.gov.
Department of Health and Human Services · USPatients First · USCedars-Sinai Medical Center · USFred Hutch Cancer Center · USSt. Jude Children's Research Hospital · USUniversity of Iowa · USUniversity of Minnesota · US

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
NATIONAL CANCER PREVENTION AND CONTROL PROGRAMU58DP000824 · DP · TEXAS STATE DEPT OF HEALTH SERVICES · PI DELGADO, EVELYN · 2007 to 2011
$44.3M
NEW YORK STATE CANCER PREVENTION & CONTROL PROGRAMU58DP003879 · DP · NYSDOH/HEALTH RESEARCH, INC. · PI WALLACE, BARBARA J · 2012 to 2014
$37.6M
Epidemiology and Natural History of Cancer-Associated VirusesZIACP010176 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MBULAITEYE, SAM M · 2009 to 2025
$33.7M
MICHIGAN CANCER PREVENTION & CONTROL PROGRAMU58DP003921 · DP · MICHIGAN STATE DEPARTMENT OF HEALTH AND HUMAN SERVICES · PI BROOKOVER, PATRICIA · 2012 to 2014
$30.7M
Category A - Communities Putting Prevention to WorkU58DP000848 · DP · COLORADO STATE DEPT/PUB HLTH & ENVIRONMT · PI JACOBELLIS, JILLIAN · 2007 to 2011
$25.9M
NATIONAL CANCER PREVENTION AND CONTROL PROGRAMU58DP000832 · DP · NC STATE DEPT/HLTH & HUMAN SERVICES · PI PETERSEN, RUTH · 2007 to 2011
$23.6M
NATIONAL CANCER PREVENTION & CONTROL PROGRAM - ILLINOISU58DP003883 · DP · ILLINOIS STATE DEPT OF PUBLIC HEALTH · PI MOODY, CONNY · 2012 to 2014
$22.6M
CALIFORNIA'S PARTICIPATION IN THE NATIONAL CANCER PREVENTION AND CONTRO PROGRAMU58DP000807 · DP · PUBLIC HEALTH INSTITUTE · PI SNIPES, KURT P · 2007 to 2011
$22.5M
GEORGIA COMPREHENSIVE CANCER CONTROL PROGRAMU58DP003875 · DP · GEORGIA DIVISION OF PUBLIC HEALTH · PI O'CONNOR, JEAN CATHERINE · 2012 to 2014
$15.9M
NEW JERSEY CANCER PREVENTION & CONTROL PROGRAMU58DP003931 · DP · NEW JERSEY STATE DEPT/HEALTH/SENIOR SRVS · PI RODRIQUEZ, GLORIA · 2012 to 2014
$11.9M
MASSACHUSETTS CANCER PREVENTION & CONTROL PROGRAMU58DP003920 · DP · MASSACHUSETTS STATE DEPT OF PUB HEALTH · PI NYAMBOSE, JOSHUA · 2012 to 2014
$11.4M
CCR NIH HHS HHSN261201300011CIntramural NIH HHS Z99 CA999999NCCDPHP CDC HHS U58 DP000807NCCDPHP CDC HHS U58 DP000824NCCDPHP CDC HHS U58 DP000832NCCDPHP CDC HHS U58 DP000848NCCDPHP CDC HHS U58 DP003875NCCDPHP CDC HHS U58 DP003879NCCDPHP CDC HHS U58 DP003883NCCDPHP CDC HHS U58 DP003920NCCDPHP CDC HHS U58 DP003921NCCDPHP CDC HHS U58 DP003931NCI NIH HHS HHSN261201000024CNCI NIH HHS HHSN261201000034CNCI NIH HHS HHSN261201000035CNCI NIH HHS HHSN261201000035INCI NIH HHS HHSN261201000036CNCI NIH HHS HHSN261201000037CNCI NIH HHS HHSN261201300011INCI NIH HHS HHSN261201300021CNCI NIH HHS HHSN261201300071CNCI NIH HHS N01 PC035137NCI NIH HHS N01 PC035139NCI NIH HHS N01 PC035142NCI NIH HHS N01 PC035143
6 · The paper itself

Abstract

Solid organ transplant recipients have increased risk for developing keratinocyte cancers, including cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), in part as a result of immunosuppressive medications administered to prevent graft rejection. In the general population, keratinocyte cancers are associated with increased risks of subsequent malignancy, however, the risk in organ transplant populations has not been evaluated. We addressed this question by linking the U.S. Scientific Registry of Transplant Recipients, which includes data on keratinocyte cancer occurrence, with 15 state cancer registries. Risk of developing malignancies after keratinocyte cancer was assessed among 118,440 Caucasian solid organ transplant recipients using multivariate Cox regression models. Cutaneous SCC occurrence (

Indexed as

Basal Cell CarcinomaCarcinoma, Squamous CellCohort StudiesHumansIncidenceKeratinocytesNeoplasms, Second PrimaryOrgan TransplantationProportional Hazards ModelsRegistriesRisk FactorsSkin NeoplasmsTransplant Recipients

Identifiers

PMID28615224
PMCPMC5540772
OpenAlexW2624696113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.