Evidence map›Paper›PMID 28615162›Full record

ArticleAmerican journal of physiology. Cell physiology2017

Characterization of muscle ankyrin repeat proteins in human skeletal muscle.

Stefan G Wette, Heather K Smith, Graham D Lamb, Robyn M Murphy

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Cell physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Titin force in muscle cells alters lattice order, thick and thin filament protein formation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  4. Review
  5. Unraveling the mysteries of the titin-N2A signalosome.The Journal of general physiology · 2021
    Article
  6. Titin N2A: More than a signaling node?The Journal of general physiology · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Differences in stability and calcium sensitivity of the Ig domains in titin's N2A region.Protein science : a publication of the Protein Society · 2020
    Article
  11. Article
  12. Article
  13. Review
  14. Titin-based mechanosensing modulates muscle hypertrophy.Journal of cachexia, sarcopenia and muscle · 2018
    Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Stefan G WetteDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.
Heather K SmithDepartment of Exercise Sciences, The University of Auckland, Auckland, New Zealand.
Graham D LambSchool of Life Sciences, La Trobe University, Melbourne, Victoria, Australia; and.
Robyn M MurphyDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia; r.murphy@latrobe.edu.au.ORCID http://orcid.org/0000-0003-3697-589X
La Trobe University · AUUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle ankyrin repeat proteins (MARPs) are a family of titin-associated, stress-response molecules and putative transducers of stretch-induced signaling in skeletal muscle. In cardiac muscle, cardiac ankyrin repeat protein (CARP) and diabetes-related ankyrin repeat protein (DARP) reportedly redistribute from binding sites on titin to the nucleus following a prolonged stretch. However, it is unclear whether ankyrin repeat domain protein 2 (Ankrd 2) shows comparable stretch-induced redistribution to the nucleus. We measured the following in rested human skeletal muscle:

Indexed as

AdultAnimalsAnkyrin RepeatFemaleHumansMuscle ProteinsMuscle, SkeletalNuclear ProteinsRatsRats, Sprague-DawleyRepressor ProteinsTissue DistributionAnkrd1 protein, ratANKRD23 protein, humanAnkrd2 protein, ratMuscle ProteinsNuclear ProteinsRepressor ProteinsAnkrd 1Ankrd 2DARPMARPprotein quantificationsingle fiberstitin

Identifiers

PMID28615162
PMCPMC5625093
OpenAlexW2624769321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.