Trial reportBMC cancer2017
Internet-based perioperative exercise program in patients with Barrett's carcinoma scheduled for esophagectomy [iPEP - study] a prospective randomized-controlled trial.
Trial report in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02478996 (Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Internet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy (iPEP Study) A Prospective Randomized-controlled Pilot Trial
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Rationales for Prehabilitation Programs in Patients Preparing for Oncologic Surgery: A Systematic Review.Annals of surgical oncology · 2026Pooled it
- Remote Exercise Training Intervention During the COVID-19 Pandemic: Randomized Controlled Trial.Journal of medical Internet research · 2024Trial
- Multimodal Web-Based Telerehabilitation for Patients With Post-COVID-19 Condition: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Association of Innate and Acquired Aerobic Capacity With Resilience in Healthy Adults: Protocol for a Randomized Controlled Trial of an 8-Week Web-Based Physical Exercise Intervention.JMIR research protocols · 2021Article
- Feasibility and implementation of a personalized, web-based exercise intervention for people with cystic fibrosis for 1 year.BMC sports science, medicine & rehabilitation · 2021Article
- The effect of EBN combined with integrated hierarchical accountability nursing on patients with severe pneumonia.American journal of translational research · 2021Article
- Strategies to prevent anastomotic leakage after esophagectomy and gastric conduit reconstruction.Langenbeck's archives of surgery · 2020Review
- Twelve-Week Internet-Based Individualized Exercise Program in Adults With Systemic Lupus Erythematosus: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2020Article
- Preoperative Nutritional Conditioning: Why, When and How.Visceral medicine · 2019Review
- [Preconditioning of the lungs and circulation before visceral and thoracic surgical interventions].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2019Review
- Web-Based Exercise as an Effective Complementary Treatment for Patients With Nonalcoholic Fatty Liver Disease: Intervention Study.Journal of medical Internet research · 2019Article
- [Preconditioning prior to visceral oncological surgery : A paradigm shift in visceral surgery?]Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Review
- [Special situations of preconditioning and prehabilitation in oncological visceral surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Review
- Individualized Web-Based Exercise for the Treatment of Depression: Randomized Controlled Trial.JMIR mental health · 2018Article
- Feasibility of using optical coherence tomography to detect radiation-induced fibrosis and residual cancer extent after neoadjuvant chemo-radiation therapy: an ex vivo study.Biomedical optics express · 2018Article
- Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials.JMIR research protocols · 2018Article
- Multidisciplinary rehabilitation across the esophageal cancer journey.Journal of thoracic disease · 2017Article
- The dawning of perioperative care in esophageal cancer.Journal of thoracic disease · 2017Article
- [Neoadjuvant therapy for tumors of the upper gastrointestinal tract : Complication management].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2015Review
- Use of a Perioperative Web-Based Exercise Program for a Patient with Barrett's Carcinoma Scheduled for Esophagectomy.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients undergoing surgery for esophageal cancer have a high risk for postoperative deterioration of lung function and pulmonary complications. This is partly due to one-lung ventilation during thoracotomy. This often accounts for prolonged stay on intensive care units, delayed postoperative reconvalescence and reduced quality of life. Socioeconomic disadvantages can result from these problems. Physical preconditioning has become a crucial leverage to optimize fitness and lung function in patients scheduled for esophagectomy, in particular during the time period of neoadjuvant therapy. METHODS/STUDY
designWe designed a prospective multicenter randomized-controlled trial. The objective is to evaluate the impact of an internet-based exercise program on postoperative respiratory parameters and pneumonia rates in patients with Barrett's carcinoma scheduled for esophagectomy. Patients are randomly assigned to either execute internet-based perioperative exercise program (iPEP), including daily endurance, resistance and ventilation training or treatment as usual (TAU). During neoadjuvant therapy and recovery, patients in the intervention group receive an individually designed intensive exercise program based on functional measurements at baseline. Personal feedback of the supervisor with customized training programs is provided in weekly intervals. DISCUSSION: This study will evaluate if an intensive individually adapted training program via online supervision during neoadjuvant therapy will improve cardiorespiratory fitness and reduce pulmonary complications following esophagectomy for Barrett's cancer.
trial registrationNCT02478996 , registered 26 May 2015.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.