Evidence map›Paper›PMID 28614950›Full record

ArticleBiointerphases2017

Grafting of architecture controlled poly(styrene sodium sulfonate) onto titanium surfaces using bio-adhesive molecules: Surface characterization and biological properties.

Hamza Chouirfa, Margaret D M Evans, David G Castner, Penny Bean, Dimitri Mercier, Anouk Galtayries, Céline Falentin-Daudré, Véronique Migonney

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biointerphases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hamza ChouirfaLBPS/CSPBAT, UMR CNRS 7244, Institut Galilée, Université Paris 13, Sorbonne Paris Cité, 99 Avenue JB Clément, 93340 Villetaneuse, France.
Margaret D M EvansCSIRO Biomedical Materials Manufacturing Program, 11 Julius Avenue, North Ryde, Sydney, NSW 2113, Australia.
David G CastnerNational ESCA and Surface Analysis Center for Biomedical Problems, Departments of Bioengineering and Chemical Engineering, University of Washington, Seattle, Washington 98195-1653.
Penny BeanCSIRO Biomedical Materials Manufacturing Program, 11 Julius Avenue, North Ryde, Sydney, NSW 2113, Australia.
Dimitri MercierPSL Research University, Chimie ParisTech-CNRS, Institut de Recherche de Chimie Paris, 75005 Paris, France.
Anouk GaltayriesPSL Research University, Chimie ParisTech-CNRS, Institut de Recherche de Chimie Paris, 75005 Paris, France.
Céline Falentin-DaudréLBPS/CSPBAT, UMR CNRS 7244, Institut Galilée, Université Paris 13, Sorbonne Paris Cité, 99 Avenue JB Clément, 93340 Villetaneuse, France.
Véronique MigonneyLBPS/CSPBAT, UMR CNRS 7244, Institut Galilée, Université Paris 13, Sorbonne Paris Cité, 99 Avenue JB Clément, 93340 Villetaneuse, France.

Funding

Surface Analysis Facility for Biomedical ProblemsP41EB002027 · NIBIB · UNIVERSITY OF WASHINGTON · PI CASTNER, DAVID G · 2003 to 2019
$17.6M
NIBIB NIH HHS P41 EB002027
6 · The paper itself

Abstract

This contribution reports on grafting of bioactive polymers such as poly(sodium styrene sulfonate) (polyNaSS) onto titanium (Ti) surfaces. This grafting process uses a modified dopamine as an anchor molecule to link polyNaSS to the Ti surface. The grafting process combines reversible addition-fragmentation chain transfer polymerization, postpolymerization modification, and thiol-ene chemistry. The first step in the process is to synthetize architecture controlled polyNaSS with a thiol end group. The second step is the adhesion of the dopamine acrylamide (DA) anchor onto the Ti surfaces. The last step is grafting polyNaSS to the DA-modified Ti surfaces. The modified dopamine anchor group with its bioadhesive properties is essential to link bioactive polymers to the Ti surface. The polymers are characterized by conventional methods (nuclear magnetic resonance, size exclusion chromatography, and attenuated total reflection-Fourier-transformed infrared), and the grafting is characterized by x-ray photoelectron spectroscopy, time-of-flight secondary ion mass spectrometry, and quartz crystal microbalance with dissipation monitoring. To illustrate the biocompatibility of the grafted Ti-DA-polyNaSS surfaces, their interactions with proteins (albumin and fibronectin) and cells are investigated. Both albumin and fibronectin are readily adsorbed onto Ti-DA-polyNaSS surfaces. The biocompatibility of modified Ti-DA-polyNaSS and control ungrafted Ti surfaces is tested using human bone cells (Saos-2) in cell culture for cell adhesion, proliferation, differentiation, and mineralization. This study presents a new, simple way to graft bioactive polymers onto Ti surfaces using a catechol intermediary with the aim of demonstrating the biocompatibility of these size controlled polyNaSS grafted surfaces.

Indexed as

Surface PropertiesAdhesivesAdsorptionAlbuminsCell AdhesionCell DifferentiationCell LineCell ProliferationChemical PhenomenaChromatography, GelCoated Materials, BiocompatibleFibronectinsHumansOsteoblastsPolystyrenesProtein BindingAdhesivesAlbuminsCoated Materials, BiocompatibleFibronectinsPolystyrenespolystyrene sulfonic acidTitanium

Identifiers

PMID28614950
PMCPMC5599117

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.