Evidence map›Paper›PMID 28614492›Full record

Trial reportRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

Clinical improvement in patients with borderline personality disorder after treatment with repetitive transcranial magnetic stimulation: preliminary results.

Julian Reyes-López, Josefina Ricardo-Garcell, Gabriela Armas-Castañeda, María García-Anaya, Iván Arango-De Montis, Jorge J González-Olvera, Francisco Pellicer

Registry-linked trialOpen access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02273674 (Repetitive Transcranial Magnetic Stimulation in Borderline Personality Disorder Patients. Effects in Clinical Measurements, Inhibition, Cognitive Flexibility, and Social Cognition Process), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02273674 nacompletednot on this map

Repetitive Transcranial Magnetic Stimulation in Borderline Personality Disorder Patients. Effects in Clinical Measurements, Inhibition, Cognitive Flexibility, and Social Cognition Process

TypeinterventionalSponsorInstituto Nacional de Psiquiatría Dr. Ramón de la FuenteRan2014 to 2016Enrolled40ConditionsBorderline Personality DisorderArmsLeft rTMS 5 Hz, Right r TMS 1 Hz
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Julian Reyes-LópezClínica del Sistema Nervioso, Departamento de Investigación Biomédica, Facultad de Medicina, Universidad Autónoma de Querétaro, Querétaro, Mexico.
Josefina Ricardo-GarcellInstituto de Neurobiología, Universidad Nacional Autónoma de México, Juriquilla, Querétaro, Mexico.
Gabriela Armas-CastañedaDepartamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad Nacional Autónoma de México, Querétaro, Mexico.
María García-AnayaInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico.
Iván Arango-De MontisInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico.
Jorge J González-OlveraInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico.
Francisco PellicerInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico.
Instituto Nacional de Psiquiatría · MXUniversidad Nacional Autónoma de México · MXAutonomous University of Queretaro · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCurrent treatment of borderline personality disorder (BPD) consists of psychotherapy and pharmacological interventions. However, the use of repetitive transcranial magnetic stimulation (rTMS) could be beneficial to improve some BPD symptoms. The objective of this study was to evaluate clinical improvement in patients with BPD after application of rTMS over the right or left dorsolateral prefrontal cortex (DLPFC).

methodTwenty-nine patients with BPD from the National Institute of Psychiatry, Mexico, were randomized in two groups to receive 15 sessions of rTMS applied over the right (1 Hz, n=15) or left (5 Hz, n=14) DLPFC. Improvement was measured by the Clinical Global Impression Scale for BPD (CGI-BPD), Borderline Evaluation of Severity Over Time (BEST), Beck Depression Inventory (BDI), Hamilton Anxiety Rating Scale (HAM-A), and Barratt Impulsiveness Scale (BIS).

resultsIntragroup comparison showed significant (p < 0.05) reductions in every psychopathologic domain of the CGI-BPD and in the total scores of all scales in both groups.

conclusionsBoth protocols produced global improvement in severity and symptoms of BPD, particularly in impulsiveness, affective instability, and anger. Further studies are warranted to explore the therapeutic effect of rTMS in BPD. CLINICAL

trial registrationNCT02273674

Indexed as

AdolescentAdultAnxiety DisordersBorderline Personality DisorderFemaleHumansMajor Depressive DisorderMaleMexicoMiddle AgedPrefrontal CortexPsychiatric Status Rating ScalesSeverity of Illness IndexTranscranial Magnetic StimulationTreatment OutcomeYoung Adult

Identifiers

PMID28614492
PMCPMC6899410
OpenAlexW2653126853

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.