ArticleOptics letters2017
Dual-axis optical coherence tomography for deep tissue imaging.
Article in Optics letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Spatially-offset optical coherence tomography (SO-OCT) for high dynamic range biological imaging at depth.Biomedical optics express · 2026Article
- From Innovation to Application: Can Emerging Imaging Techniques Transform Breast Cancer Diagnosis?Diagnostics (Basel, Switzerland) · 2025Review
- Indocyanine green (ICG) enhances penetration of 1300 nm optical coherence tomography imaging forOptics letters · 2025Article
- Enhanced penetration depth in optical coherence tomography and photoacoustic microscopyOptica · 2025Article
- Optical clearing with tartrazine enables deep transscleral imaging with optical coherence tomography.Journal of biomedical optics · 2024Article
- Spatially offset optical coherence tomography: Leveraging multiple scattering for high-contrast imaging at depth in turbid media.Science advances · 2023Article
- Nontoxic Fluorescent Nanoprobes for Multiplexed Detection and 3D Imaging of Tumor Markers in Breast Cancer.Pharmaceutics · 2023Review
- Using beam-offset optical coherence tomography to reconstruct backscattered photon profiles in scattering media.Biomedical optics express · 2022Article
- Metasurface-based bijective illumination collection imaging provides high-resolution tomography in three dimensions.Nature photonics · 2022Article
- Deep imaging with 1.3 µm dual-axis optical coherence tomography and an enhanced depth of focus.Biomedical optics express · 2021Article
- Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus.Annals of the New York Academy of Sciences · 2020Review
- Advances in Doppler optical coherence tomography and angiography.Translational biophotonics · 2019Article
- Off-axis spatiotemporally gated multimode detection toward deep fog imaging.Optics express · 2019Article
- Advanced Imaging for Barrett's Esophagus and Early Neoplasia: Surface and Subsurface Imaging for Diagnosis and Management.Current gastroenterology reports · 2018Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
We have developed dual-axis optical coherence tomography (DA-OCT) which enables deep tissue imaging by using a novel off-axis illumination/detection configuration. DA-OCT offers a 100-fold speed increase compared with its predecessor, multispectral multiple-scattering low coherence interferometry (ms2/LCI), by using a new beam scanning mechanism based on a microelectro-mechanical system (MEMS) mirror. The data acquisition scheme was altered to take advantage of this scanning speed, producing tomographic images at a rate of 4 frames (B-scans) per second. DA-OCT differs from ms2/LCI in that the dual axes intersect at a shallower depth (∼1 mm). This difference, coupled with the faster scanning speed, shifts the detection priority from multiply scattered to ballistic light. The utility of this approach was demonstrated by imaging both ex vivo porcine ear skin and in vivo rat skin from a McFarlane flap model. The enhanced penetration depth provided by the DA-OCT system will be beneficial to various clinical applications in dermatology and surgery.
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