ArticleNature2017
BAP1 regulates IP3R3-mediated Ca
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In one paragraph
Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 226 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
226citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
226 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature.Journal of gastrointestinal cancer · 2024Pooled it
- Digital PCR for Detecting Loss of BAP1 and MTAP in Pleural Fluids of Mesothelioma Patients: Perspectives in the Diagnosis.Pathology international · 2026Article
- Identification of disulfidptosis-related molecular subtypes in pleural mesothelioma demonstrates a correlation with the immune infiltration, prognosis and therapy efficacy.Discover oncology · 2026Article
- Research progress on the regulation of mesothelioma driven by deubiquitinating enzyme BAP1.Clinical and experimental medicine · 2026Review
- Recent advances in the molecular genetic mechanisms and immune microenvironment of uveal melanoma.Melanoma research · 2026Review
- Regulation of ferroptosis by BAP1.Cell death and differentiation · 2026Article
- Allosteric network of dynamic coupling within BAP1-UCH revealed by methyl NMR.Nature communications · 2026Article
- Functional characterization of BAP1 mutations in genome edited cholangiocarcinoma organoids: Role in cell death and drug responses.iScience · 2026Article
- Structural basis of nucleosome deubiquitination by the bidentate Calypso/Asx complex.iScience · 2026Article
- The spatiotemporal dynamics of MAMs: mechanisms, pathologies, and therapeutic rewiring.Cellular & molecular biology letters · 2026Review
- ROS-responsive Ganoderma lucidum polysaccharide nanocomposite targeting prosenescent oxidative stress niche for structural and functional diabetic tendon regeneration.Journal of nanobiotechnology · 2026Article
- BRCA1-Associated Protein 1 (BAP1) in Human Cancer and its Emerging Role as a Novel Potential Therapeutic Target.Current oncology reports · 2026Review
- BAP1 Loss Induces Senescence and Enhances the Response to Radiation Therapy and Senolytics.bioRxiv : the preprint server for biology · 2026Article
- Mitochondria-ER crosstalk via MAMS: Bridging cellular homeostasis and cancer progression.Apoptosis : an international journal on programmed cell death · 2026Review
- The role of mitochondria-endoplasmic reticulum crosstalk in colorectal cancer.Genes & diseases · 2026Review
- Prognostic value of BAP1 expression in uveal melanoma: a comparative study with histopathological factors in a large Spanish cohort.Frontiers in oncology · 2026Article
- Tumor suppressor BAP1 emerges as a key regulator of metabolism and cell death in tumors.Frontiers in cell and developmental biology · 2026Review
- MicroRNA profiling in post-mortem spinal cord of C9ORF72-related ALS patients reveals molecular pathways involved in motor neuron degeneration.Frontiers in neuroscience · 2026Article
- Advances in the Basic Sciences in Thoracic Oncology in the Last 20 Years and Their Translational Impact.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2026Review
- Knockdown of PR-DUB subunit calypso in the developing Drosophila eye and wing results in mis-patterned tissues with altered size and shape.G3 (Bethesda, Md.) · 2025Article
166 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
25 authors.
Angela BononiUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Carlotta GiorgiDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, 44121 Italy.
Simone PatergnaniDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, 44121 Italy.
David LarsonUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Kaitlyn VerbruggenUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Mika TanjiUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Laura PellegriniUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Valentina SignoratoUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Federica OlivettoUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Sandra PastorinoUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Masaki NasuUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Andrea NapolitanoUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Giovanni GaudinoUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Paul MorrisUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Greg SakamotoUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Laura K FerrisDepartment of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, 15213 USA.
Alberto DaneseDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, 44121 Italy.
Andrea RaimondiExperimental Imaging Center, San Raffaele Scientific Institute Milano, 20132 Italy.
Carlo TacchettiExperimental Imaging Center, San Raffaele Scientific Institute Milano, 20132 Italy.
Shafi KuchayCancer Center, New York University, New York, New York 10016, USA.
Harvey I PassCancer Center, New York University, New York, New York 10016, USA.
El Bachir AffarMaisonneuve-Rosemont Hospital Research Center, Department of Medicine, University of Montréal, Montréal, Quebec H1T 2M4, Canada.
Haining YangUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Paolo PintonDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, 44121 Italy.
Michele CarboneUniversity of Hawaii Cancer Center, University of Hawaii, Honolulu, Hawaii 96813 USA.
Funding
University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2MGermline BAP1 Mutations and Malignant Mesothelioma: Mechanisms and Early DetectionR01CA198138 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI CARBONE, MICHELE · 2015 to 2019
$1.7MThe Role of HMGB1 in the Pathogenesis of MesotheliomaR01CA160715 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI YANG, HAINING · 2011 to 2015
$1.5MNCI NIH HHS P30 CA071789NCI NIH HHS R01 CA160715NCI NIH HHS R01 CA198138
Abstract
BRCA1-associated protein 1 (BAP1) is a potent tumour suppressor gene that modulates environmental carcinogenesis. All carriers of inherited heterozygous germline BAP1-inactivating mutations (BAP1
Indexed as
Cell Transformation, NeoplasticApoptosisAsbestosCalciumCalcium SignalingCell NucleusCells, CulturedCell SurvivalCytoplasmDNA DamageEndoplasmic ReticulumEpitheliumFibroblastsGene-Environment InteractionHumansInositol 1,4,5-Trisphosphate ReceptorsAsbestosBAP1 protein, humanCalciumInositol 1,4,5-Trisphosphate ReceptorsITPR3 protein, humanTumor Suppressor ProteinsUbiquitinUbiquitin Thiolesterase
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.