Observational studyAnesthesiology2017
Pain Catastrophizing Moderates Relationships between Pain Intensity and Opioid Prescription: Nonlinear Sex Differences Revealed Using a Learning Health System.
Observational study in Anesthesiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04994249 (Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain), which is not on this map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation
Who cites it
40 citing papers in PubMed, 76 citations in OpenAlex.
- Trait impulsivity prospectively predicts lower methadone treatment retention: moderation by pain catastrophizing.Addiction science & clinical practice · 2026Observational
- Effects of biopsychosocial complexity and pain-related factors on opioid prescription in patients with chronic musculoskeletal pain.Pain reports · 2025Article
- Reply to the letter by Guoying Wang.Journal of anesthesia · 2025Article
- Maladaptive Compensatory Neural Mechanisms Associated with Activity-Related Osteoarthritis Pain: Dissociation of Psychological and Activity-Related Neural Mechanisms of WOMAC Pain and VAS Pain.Journal of clinical medicine · 2025Article
- Development and preliminary testing of a comprehensive Ecological Momentary Assessment of people with chronic pain.The journal of pain · 2025Article
- Zoom-Delivered Empowered Relief for Chronic Pain: Observational Longitudinal Pilot Study Exploring Feasibility and Pain-Related Outcomes in Patients on Long-Term Opioids.JMIR formative research · 2025Observational
- The effects of frailty on opioid consumption after total knee arthroplasty.Journal of anesthesia · 2025Article
- Article
- Opioid use patterns following discharge from elective colorectal surgery: a prospective cohort study.Surgical endoscopy · 2025Article
- Article
- Utilizing a learning health system to capture real-world patient data: Application of the reliable change index to evaluate and improve the outcome of a pain rehabilitation program.Pain practice : the official journal of World Institute of Pain · 2024Article
- The relationship between emotion regulation and pain catastrophizing in patients with chronic pain.Pain medicine (Malden, Mass.) · 2024Article
- Article
- Pain catastrophizing, pain anxiety, and substance use among Black individuals with chronic pain who use opioids.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023Article
- Opioid coping motives and pain intensity among adults with chronic low back pain: associations with mood, pain reactivity, and opioid misuse.Journal of behavioral medicine · 2023Article
- Prescription and consumption of opioids after bariatric surgery: a multicenter prospective cohort study.Surgical endoscopy · 2023Article
- Individual Dimensions of Pain Catastrophizing Do Not Mediate the Effect of Sociodemographic and Psychological Factors on Chronic Orofacial Pain Severity, Interference, and Jaw Limitation: A Structural Equation Modeling Approach.The journal of pain · 2023Article
- Pragmatic Comparative Effectiveness Trials and Learning Health Systems in Pain Medicine: Opportunities and Challenges.Anesthesiology clinics · 2023Review
- Psychological Evaluation of Patients With Cancer Presenting to the Emergency Department With Pain: Independent Predictors of Worse Pain Severity, Interference, and Higher Hourly Opioid Administration.JCO oncology practice · 2022Article
- CHOIRBM: An R package for exploratory data analysis and interactive visualization of pain patient body map data.PLoS computational biology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundPain catastrophizing is a maladaptive response to pain that amplifies chronic pain intensity and distress. Few studies have examined how pain catastrophizing relates to opioid prescription in outpatients with chronic pain.
methodsThe authors conducted a retrospective observational study of the relationships between opioid prescription, pain intensity, and pain catastrophizing in 1,794 adults (1,129 women; 63%) presenting for new evaluation at a large tertiary care pain treatment center. Data were sourced primarily from an open-source, learning health system and pain registry and secondarily from manual review of electronic medical records. A binary opioid prescription variable (yes/no) constituted the dependent variable; independent variables were age, sex, pain intensity, pain catastrophizing, depression, and anxiety.
resultsMost patients were prescribed at least one opioid medication (57%; n = 1,020). A significant interaction and main effects of pain intensity and pain catastrophizing on opioid prescription were noted (P < 0.04). Additive modeling revealed sex differences in the relationship between pain catastrophizing, pain intensity, and opioid prescription, such that opioid prescription became more common at lower levels of pain catastrophizing for women than for men.
conclusionsResults supported the conclusion that pain catastrophizing and sex moderate the relationship between pain intensity and opioid prescription. Although men and women patients had similar Pain Catastrophizing Scale scores, historically "subthreshold" levels of pain catastrophizing were significantly associated with opioid prescription only for women patients. These findings suggest that pain intensity and catastrophizing contribute to different patterns of opioid prescription for men and women patients, highlighting a potential need for examination and intervention in future studies.
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