Evidence map›Paper›PMID 28612755›Full record

ReviewJournal of neural engineering2017

Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies.

Michael Beyeler, Ariel Rokem, Geoffrey M Boynton, Ione Fine

Abstract readReview
In one paragraph

Review in Journal of neural engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
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  6. Neural population dynamics of direct electrical stimulation of neocortex.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
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  12. Static or Temporal? Semantic Scene Simplification to Aid Wayfinding in Immersive Simulations of Bionic Vision.Proceedings of the ACM Symposium on Virtual Reality Software and Technology. ACM Symposium on Virtual Reality Software and Technology · 2025
    Article
  13. Aligning Visual Prosthetic Development With Implantee Needs.Translational vision science & technology · 2024
    Article
  14. Aligning visual prosthetic development with implantee needs.medRxiv : the preprint server for health sciences · 2024
    Article
  15. Article
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  20. Towards aJournal of neural engineering · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael BeyelerDepartment of Psychology, University of Washington, Seattle, WA, United States of America.ORCID 0000-0001-5233-844X
Ariel RokemInstitute for Neuroengineering, University of Washington, Seattle, WA, United States of America.ORCID 0000-0003-0679-1985
Geoffrey M BoyntonDepartment of Psychology, University of Washington, Seattle, WA, United States of America.ORCID 0000-0001-6561-6920
Ione FineDepartment of Psychology, University of Washington, Seattle, WA, United States of America.ORCID 0000-0002-0142-7239

Funding

The Effects of Attention in Human Visual CortexR01EY012925 · NEI · UNIVERSITY OF WASHINGTON · PI BOYNTON, GEOFFREY M · 1999 to 2018
$5.6M
The Effects of Visual DeprivationR01EY014645 · NEI · UNIVERSITY OF WASHINGTON · PI FINE, IONE · 2004 to 2021
$5.3M
NEI NIH HHS R01 EY012925NEI NIH HHS R01 EY014645
6 · The paper itself

Abstract

The 'bionic eye'-so long a dream of the future-is finally becoming a reality with retinal prostheses available to patients in both the US and Europe. However, clinical experience with these implants has made it apparent that the visual information provided by these devices differs substantially from normal sight. Consequently, the ability of patients to learn to make use of this abnormal retinal input plays a critical role in whether or not some functional vision is successfully regained. The goal of the present review is to summarize the vast basic science literature on developmental and adult cortical plasticity with an emphasis on how this literature might relate to the field of prosthetic vision. We begin with describing the distortion and information loss likely to be experienced by visual prosthesis users. We then define cortical plasticity and perceptual learning, and describe what is known, and what is unknown, about visual plasticity across the hierarchy of brain regions involved in visual processing, and across different stages of life. We close by discussing what is known about brain plasticity in sight restoration patients and discuss biological mechanisms that might eventually be harnessed to improve visual learning in these patients.

Indexed as

Visual ProsthesisHumansLearningNeuronal PlasticityOptogeneticsVisual CortexVisual Perception

Identifiers

PMID28612755
PMCPMC5953572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.