ArticleBioMedicine2017
Genetic characteristic of class 1 integrons in proteus mirabilis isolates from urine samples.
Article in BioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 41 citations in OpenAlex.
- Emergence of extensive drug resistance and high prevalence of multidrug resistance among clinical Proteus mirabilis isolates in Egypt.Annals of clinical microbiology and antimicrobials · 2024Article
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- Epidemiology of extended-spectrum β-lactamases inFrontiers in microbiology · 2022Review
- Prevalence, antibiotic profile, virulence determinants, ESBLs, and non-β-lactam encoding genes of MDRFrontiers in genetics · 2022Article
- Genomic Investigation ofFrontiers in microbiology · 2022Article
- From the Urinary Catheter to the Prevalence of Three Classes of Integrons,BioMed research international · 2021Article
- Screening of antibiotic resistance genes in pathogenic bacteria isolated from tiny freshwater shrimp (Journal of advanced veterinary and animal research · 2020Article
- Impacts of RETN genetic polymorphism on breast cancer development.Journal of Cancer · 2020Article
- Association between colorectal cancer and thiazolidinediones administration in a case-control study.BioMedicine · 2019Article
- Association between oral corticosteroid use and pyogenic liver abscesses in a case-control study.BioMedicine · 2018Article
- Correlation betweenInternational journal of medical sciences · 2018Article
- Population-based cohort study investigating the association between weight loss and pyogenic liver abscesses.BioMedicine · 2017Article
- Nationwide Case-Control Study Examining the Association between Tamoxifen Use and Alzheimer's Disease in Aged Women with Breast Cancer in Taiwan.Frontiers in pharmacology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProteus mirabilis is an opportunistic pathogen, commonly associated with complicated urinary tract infections (UTIs). UTIs caused by multidrug-resistant Proteus mirabilis have increased worldwide. Multidrug-resistance of Gram-negative enteric bacteria is usually associated with class 1 integrons. PURPOSES: To investigate the prevalence and characterize gene cassettes of class 1 integrons in multidrug-resistant P. mirabilis Methods: From 2006 to 2008, 314 P. mirabilis isolates from urine were collected from a regional teaching hospital. Antimicrobial resistance of the isolates was determined by disk diffusion methods. The phenotypic confirmatory test of extended-spectrum β-lactamase (ESBL) production was performed as described in the Clinical and Laboratory Standards Institute (CLSI) guideline. The genetic organization of the class 1 integron cassettes was investigated by PCR, cloning, and sequencing of the regions surrounding these genes.
resultsSeventy-nine (25%, 79/314) P. mirabilis isolates were ESBL-producing and most ESBL-producing P. mirabilis were positive for bla
conclusionThis study investigated the prevalence and characterized gene cassettes of class 1 integrons in MDR P. mirabilis isolates from urine samples. The frequency of gene cassettes in P. mirabilis were partially by clonal spread of the carriers and the results could provide information for effective antimicrobial therapy and infection control.
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