Trial reportJournal of clinical hypertension (Greenwich, Conn.)2017
Obesity and the diagnostic accuracy for primary aldosteronism.
Trial report in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Obesity and the diagnostic accuracy for primary aldosteronism.Journal of clinical hypertension (Greenwich, Conn.) · 2017Trial
- Effect of a Prior Two-Hour Postural Test on Seated Saline Suppression Test Results in Patients Predominantly Evaluated for Adrenal Incidentalomas.Journal of clinical medicine · 2026Article
- The Burden, Outcomes, and Management of Patients with Aldosterone Dysregulation: A Targeted Literature Review.Advances in therapy · 2026Review
- Genetic evidence for the causal relationship between metabolic diseases and primary aldosteronism: insights from Mendelian randomization analysis.Cardiovascular endocrinology & metabolism · 2026Article
- Association between serum uric acid levels and primary aldosteronism.BMC nephrology · 2025Article
- Effect of Obesity on Clinical Characteristics of Primary Aldosteronism Patients at Diagnosis and Postsurgical Response.The Journal of clinical endocrinology and metabolism · 2023Article
- Glucose Alterations, Insulin Resistance, Arterial Hypertension, and Renin are Strictly Associated in Pediatric Obesity.Journal of the Endocrine Society · 2023Article
- Confounders of the aldosterone-to-renin ratio when used as a screening test in hypertensive patients: A critical analysis of the literature.Journal of clinical hypertension (Greenwich, Conn.) · 2021Review
- High body fat percentage is associated with primary aldosteronism: a cross-sectional study.BMC endocrine disorders · 2020Article
- Relationship Between Visceral Fat and Plasma Aldosterone Concentration in Patients With Primary Aldosteronism.Journal of the Endocrine Society · 2018Article
- Bypass of confirmatory tests for case detection of primary aldosteronism in leaner patients?Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
The effects of body mass index on the diagnostic accuracy of primary aldosteronism (PA) are inconsistent and yet important considering the high prevalence and frequent co-occurrence of obesity and hypertension. The current study included 59 adult patients who underwent a stepwise evaluation for PA, using aldosterone to renin ratio for case detection and plasma aldosterone concentration after saline suppression test and/or 24-hour urinary aldosterone after oral sodium loading for case confirmation. Body mass index had a quadratic (U-shaped) correlation with plasma aldosterone concentration, plasma renin activity, aldosterone to renin ratio, and plasma aldosterone concentration after saline suppression test. Among patients with a body mass index ≥30 kg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.