ReviewCurrent rheumatology reports2017
Cocaine-Levamisole-Induced Vasculitis/Vasculopathy Syndrome.
Review in Current rheumatology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 68 citations in OpenAlex.
- Cocaine-Levamisole-Associated Vasculopathy Mimicking ANCA-Associated Vasculitis and Presenting With Pulmonary-Renal Syndrome Requiring VV-ECMO Support.The American journal of case reports · 2026Article
- Cocaine- and Levamisole-Induced Vasculitis (CLIV).Cureus · 2025Review
- Cocaine-Triggered PR3-ANCA Vasculitis Localized to a Post-Surgical Neck Field: A Case of Locus Minoris Resistentiae in Drug-Induced Autoimmunity.Diagnostics (Basel, Switzerland) · 2025Article
- Comprehensive Management of Cocaine-Induced Midline Destructive Lesions: A Young-IfOS Consensus.Journal of personalized medicine · 2025Article
- Retinal Vascular Complications in Cocaine Abuse: A Case Report and a Literature Review.Journal of clinical medicine · 2024Review
- Cocaine- and Levamisole-Induced Vasculitis: Defining the Spectrum of Autoimmune Manifestations.Journal of clinical medicine · 2024Review
- Granulomatosis with polyangiitis or its mimic? A case report.The Journal of international medical research · 2024Article
- Mucocutaneous Manifestations of Recreational Drug Use.American journal of clinical dermatology · 2024Review
- Everything but the Kitchen Sink: An Analysis of Bacterial and Chemical Contaminants Found in Syringe Residue From People Who Inject Drugs.Open forum infectious diseases · 2024Article
- Pulmonary-Renal Syndrome from Levamisole-Adulterated Cocaine-Induced Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Cocaine/Levamisole-Induced, Skin-Limited ANCA-Associated Vasculitis with Pyoderma Gangrenosum-like Presentation.Dermatopathology (Basel, Switzerland) · 2022Article
- Leukocytoclastic Vasculitis Induced by Cocaine Adulterated with Levamisole.European journal of case reports in internal medicine · 2022Article
- Surgical management and outcomes of levamisole-induced vasculitis in a burn center: A case series.JAAD case reports · 2021Article
- Cocaine-Induced Midline Destructive Lesions: A Real Challenge in Oral Rehabilitation.International journal of environmental research and public health · 2021Article
- MOG-IgG-associated demyelination: focus on atypical features, brain histopathology and concomitant autoimmunity.Journal of neurology · 2020Observational
- Drug-induced anti-neutrophil cytoplasmic antibody-associated vasculitis.Chinese medical journal · 2019Review
- ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives.Journal of immunology research · 2019Review
- Multiple cutaneous and mucosal lesions in a patient with cocaine-levamisole-induced vasculopathy syndrome.Proceedings (Baylor University. Medical Center) · 2019Article
- A Case of Cutaneous Vasculitis in the Setting of Systemic Lupus Erythematosus and Cocaine Use.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo understand the clinical spectrum of cocaine-levamisole-induced vasculitis. Worldwide recreational drug consumption is high among the adult population from various social strata. The use of cocaine with levamisole, a frequently added antiparasitic diluent, favors the manifestations of vasculitic lesions, especially in the skin. RECENT
findingsNew insights into immunological mechanisms involved in the pathogenesis of the disease. There are still many unknown aspects in the pathogenesis of this disease, such as the immune system interaction with p-ANCAs and the release of inflammatory NETs (neutrophil extracellular traps), which are the origin of auto-antigens and tissue damage, manifesting as vasculitic purpura on the skin. The clinical presentation constitutes a challenge for the clinician to be able to distinguish it from small-vessel vasculitides. This paper intends to improve the understanding of this condition, exhibiting the broad clinical spectrum of local and systemic manifestations of cocaine-levamisole-induced vasculitis, to facilitate a timely diagnosis, in order to take corrective measures and avoid sequelae, along with tissue damage and the consequent deformities and permanent scars.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.