Evidence map›Paper›PMID 28612318›Full record

ReviewNeuroscience bulletin2018

Somatosensory Neuron Typing with High-Coverage Single-Cell RNA Sequencing and Functional Analysis.

Changlin Li, Sashuang Wang, Yan Chen, Xu Zhang

Open access · hybridAbstract readReview
In one paragraph

Review in Neuroscience bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Neuroimmune interactions in atopic and allergic contact dermatitis.The Journal of allergy and clinical immunology · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Peripheral Mechanisms of Itch.The Journal of investigative dermatology · 2022
    Review
  13. FcεR1-expressing nociceptors trigger allergic airway inflammation.The Journal of allergy and clinical immunology · 2021
    Article
  14. TRPV1 in Pain and Itch.Advances in experimental medicine and biology · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Changlin LiInstitute of Neuroscience and State Key Laboratory of Neuroscience, Center for Excellence in Brain Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Sashuang WangInstitute of Neuroscience and State Key Laboratory of Neuroscience, Center for Excellence in Brain Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Yan ChenInstitute of Neuroscience and State Key Laboratory of Neuroscience, Center for Excellence in Brain Science, Chinese Academy of Sciences, Shanghai, 200031, China.
Xu ZhangInstitute of Neuroscience and State Key Laboratory of Neuroscience, Center for Excellence in Brain Science, Chinese Academy of Sciences, Shanghai, 200031, China. xu.zhang@ion.ac.cn.
Chinese Academy of Sciences · CNShanghaiTech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different physical and chemical stimuli are detected by the peripheral sensory receptors of dorsal root ganglion (DRG) neurons, and the generated inputs are transmitted via afferent fibers into the central nervous system. The gene expression profiles of DRG neurons contribute to the generation, transmission, and regulation of various somatosensory signals. Recently, the single-cell transcriptomes, cell types, and functional annotations of somatosensory neurons have been studied. In this review, we introduce our classification of DRG neurons based on single-cell RNA-sequencing and functional analyses, and discuss the technical approaches. Moreover, studies on the molecular and cellular mechanisms underlying somatic sensations are discussed.

Indexed as

AnimalsGanglia, SpinalGene Regulatory NetworksHumansPainSensory Receptor CellsSequence Analysis, RNATranscriptomeGene profilesNeuron typePainSingle-cell technologySomatosensory mechanism

Identifiers

PMID28612318
PMCPMC5799126
OpenAlexW2627046609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.