Evidence map›Paper›PMID 28612247›Full record

ReviewAnnals of nuclear medicine2017

Alexandra Nikaki, George Angelidis, Roxani Efthimiadou, Ioannis Tsougos, Varvara Valotassiou, Konstantinos Fountas, Vasileios Prasopoulos, Panagiotis Georgoulias

Abstract readReview
In one paragraph

Review in Annals of nuclear medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Olfactory Drug Delivery in Rodents: Deposition and Pharmacokinetics.ACS pharmacology & translational science · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Complex Diagnostic Challenges in Glioblastoma: The Role ofPharmaceuticals (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Glioblastoma Metabolism: Insights and Therapeutic Strategies.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Automated Optimized Synthesis of [Molecules (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Simultaneous Mapping of Vasculature, Hypoxia, and Proliferation Using Dynamic Susceptibility Contrast MRI,Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  13. Article
  14. Correlation of 4'-[methyl-EJNMMI research · 2021
    Article
  15. Targeting VPAC1 Receptors for Imaging Glioblastoma.Molecular imaging and biology · 2020
    Article
  16. European journal of hybrid imaging · 2020
    Article
  17. Frontiers in neuroscience · 2020
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra NikakiDepartment of Clinical Physiology, KHSHP, 20 Ahvenistontie Str., 13530, Hämeenlinna, Finland.
George AngelidisDepartment of Nuclear Medicine, University Hospital of Larissa, Mezourlo, 41110, Larissa, Greece.
Roxani EfthimiadouPET/CT Department, Hygeia Hospital, 4 Erythrou Stavrou Str., 15123, Athens, Greece.
Ioannis TsougosDepartment of Nuclear Medicine, University Hospital of Larissa, Mezourlo, 41110, Larissa, Greece.
Varvara ValotassiouDepartment of Nuclear Medicine, University Hospital of Larissa, Mezourlo, 41110, Larissa, Greece.
Konstantinos FountasDepartment of Neurosurgery, University Hospital of Larissa, Mezourlo, 41110, Larissa, Greece.
Vasileios PrasopoulosPET/CT Department, Hygeia Hospital, 4 Erythrou Stavrou Str., 15123, Athens, Greece.
Panagiotis GeorgouliasDepartment of Nuclear Medicine, University Hospital of Larissa, Mezourlo, 41110, Larissa, Greece. pgeorgoul@med.uth.gr.ORCID http://orcid.org/0000-0001-7331-7250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain neoplasms constitute a group of tumors with discrete differentiation grades, and therefore, course of disease and prognosis. Magnetic resonance imaging (MRI) remains the gold standard method for the investigation of central nervous system tumors. However, MRI suffers certain limitations, especially if radiation therapy or chemotherapy has been previously applied. On the other hand, given the development of newer radiopharmaceuticals, positron emission tomography (PET) aims to a better investigation of brain tumors, assisting in the clinical management of the patients. In the present review, the potential contribution of radiolabeled fluorothymidine (FLT) imaging for the evaluation of brain tumors will be discussed. In particular, we will present the role of FLT-PET imaging in the depiction of well and poorly differentiated lesions, the assessment of patient prognosis and treatment response, and the recognition of disease recurrence. Moreover, related semi-quantitative and kinetic parameters will be discussed.

Indexed as

DideoxynucleosidesBiomarkers, TumorGliomaHumansNeoplasm GradingPositron-Emission TomographyTreatment OutcomealovudineBiomarkers, TumorDideoxynucleosidesFluorothymidineGliomaMRIPETPrognosis

Identifiers

PMID28612247
PMCPMC5517561

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.