Evidence map›Paper›PMID 28612215›Full record

ArticleAIDS and behavior2018

The Role of Financial Incentives Along the Antiretroviral Therapy Adherence Continuum: A Qualitative Sub-study of the HPTN 065 (TLC-Plus) Study.

Elizabeth E Tolley, Jamilah Taylor, Allison Pack, Elizabeth Greene, Jill Stanton, Victoria Shelus, Richard Dunner, Theo Hodge, Bernard Branson, Wafaa M El-Sadr and 1 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elizabeth E TolleyBehavioral, Epidemiological & Clinical Sciences Division, FHI 360, 359 Blackwell Street, Suite 200, Durham, NC, 27701, USA. btolley@fhi360.org.ORCID 0000-0002-9823-3675
Jamilah TaylorBehavioral, Epidemiological & Clinical Sciences Division, FHI 360, 359 Blackwell Street, Suite 200, Durham, NC, 27701, USA.
Allison PackHealth Behavior Department, Gillings School of Public Health, University of North Carolina, Chapel Hill, NC, USA.
Elizabeth GreeneScience Facilitation, FHI 360, 359 Blackwell St, Durham, NC, USA.
Jill StantonScience Facilitation, FHI 360, 359 Blackwell St, Durham, NC, USA.
Victoria ShelusInstitute for Reproductive Health, Georgetown University, Washington, DC, USA.
Richard DunnerNarco Freedom, Bronx, NY, USA.
Theo HodgeCapital Medical, Washington, DC, USA.
Bernard BransonScientific Affairs LLC, Atlanta, GA, USA.
Wafaa M El-SadrICAP at Columbia University, New York, NY, USA.
Theresa GambleScience Facilitation, FHI 360, 359 Blackwell St, Durham, NC, USA.

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI MYRON Scott COHEN, Sinead Delany-Moretlwe · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619
6 · The paper itself

Abstract

The stages of change (SOC) theory suggests individuals adapt incrementally to behaviors like adherence, requiring different strategies over the behavior change continuum. Offering financial incentives (FIs) is one strategy to motivate adherence. This qualitative sub-study examined adherence barriers and the role of FIs to increase viral suppression (VS) among HIV Prevention Trials Network (HPTN) 065 study participants categorized into SOC-related adherence stages based on changes from baseline to follow-up viral load tests. Of 73 participants, most were in Maintenance stage (n = 31), defined as having achieved VS throughout HPTN 065, or in Action stage (n = 29), defined as moving from virally unsuppressed to suppressed in 50% or more of tests. Only 13 were Low Adherers, having achieved VS in fewer than 50% of tests. The latter group faced substantial social and structural adherence barriers. Participants in the Action stage made positive changes to adherence routines to achieve VS. Those in Maintenance were less incentivized by FIs, as they were already committed. Results from this sub-study suggest FI effectiveness may vary across the SOC continuum, with greatest impact for those initiating antiretroviral or without explicit adherence routines. FIs may be insufficient to overcome strong social or structural barriers, and unnecessary for those intrinsically committed to remaining adherent.

Indexed as

Antiretroviral Therapy, Highly ActiveMedication AdherenceMotivationRemunerationAdultAnti-Retroviral AgentsFemaleHIV InfectionsHumansMaleMiddle AgedNorth CarolinaPain ManagementQualitative ResearchViral LoadYoung AdultAnti-Retroviral AgentsAdherenceFinancial incentivesHIVStage of changeUnited States

Identifiers

PMID28612215
PMCPMC5758676

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.