Evidence map›Paper›PMID 28612057›Full record

ReviewInvestigative and clinical urology2017

Imaging studies and biomarkers to detect clinically meaningful vesicoureteral reflux.

Michaella Maloney Prasad, Earl Y Cheng

Open access · diamondAbstract readReview
In one paragraph

Review in Investigative and clinical urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Pediatric vesicoureteral reflux: Slow but steady steps.Investigative and clinical urology · 2017
    Article
  7. Article
  8. Primary Vesicoureteral reflux and chronic kidney disease in pediatric population. What we have learnt?International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Michaella Maloney PrasadMedical University of South Carolina, Charleston, SC, USA.
Earl Y ChengAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
Lurie Children's Hospital · USMedical University of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The work-up of a febrile urinary tract infection is generally performed to detect vesicoureteral reflux (VUR) and its possible complications. The imaging modalities most commonly used for this purpose are renal-bladder ultrasound, voiding cystourethrogram and dimercapto-succinic acid scan. These studies each contribute valuable information, but carry individual benefits and limitations that may impact their efficacy. Biochemical markers are not commonly used in pediatric urology to diagnose or differentiate high-risk disease, but this is the emerging frontier, which will hopefully change our approach to VUR in the future. As it becomes more apparent that there is tremendous clinical variation within grades of VUR, the need to distinguish clinically significant from insignificant disease grows. The unfortunate truth about VUR is that recommendations for treatment may be inconsistent. Nuances in clinical decision-making will always exist, but opinions for medical versus surgical intervention should be more standardized, based on risk of injury to the kidney.

Indexed as

BiomarkersHumansKidneyMagnetic Resonance ImagingRadionuclide ImagingUltrasonographyUrinary Tract InfectionsUrographyVesico-Ureteral RefluxBiomarkersBiomarkersTechnetium Tc 99m dimercaptosuccinic acidUrinary tract infectionsUrographyVesicoureteral reflux

Identifiers

PMID28612057
PMCPMC5468261
OpenAlexW2621675412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.