ReviewInvestigative and clinical urology2017
Genetics of vesicoureteral reflux and congenital anomalies of the kidney and urinary tract.
Review in Investigative and clinical urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Review
- Urological Malformations Identify the High-Burden Phenotype Among Children Hospitalized for Presumed Urinary Tract Infection: A Retrospective Cohort.Diagnostics (Basel, Switzerland) · 2026Article
- The causes and consequences of paediatric kidney disease on adult nephrology care.Pediatric nephrology (Berlin, Germany) · 2022Review
- A Premature Baby with Severe Oligohydramnios and Hypotension: a Case Report of Renal Tubular Dysgenesis.Journal of Korean medical science · 2020Article
- Review
- Unique association of multiple endocrine neoplasia 2A and congenital anomalies of the kidney and urinary tract in a child with aBMJ case reports · 2019Article
- Pediatric vesicoureteral reflux: Slow but steady steps.Investigative and clinical urology · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The definition of congenital anomalies of the kidney and urinary tract (CAKUT) is the disease of structural malformations in the kidney and/or urinary tract containing vesicoureteral reflux (VUR). These anomalies can cause pediatric chronic kidney disease. However, the pathogenesis of CAKUT is not well understood, because identifying the genetic architecture of CAKUT is difficult due to the phenotypic heterogeneity and multifactorial genetic penetrance. We describe the current genetic basis and mechanisms of CAKUT including VUR via approaching the steps and signaling pathways of kidney developmental processes. We also focus on the newly developed strategies and challenges to fully address the role of the associated genes in the pathogenesis of the disease.
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