Evidence map›Paper›PMID 28612052›Full record

ArticleWellcome open research2016

A CRISPR/Cas9-based method and primer design tool for seamless genome editing in fission yeast.

María Rodríguez-López, Cristina Cotobal, Oscar Fernández-Sánchez, Natalia Borbarán Bravo, Risky Oktriani, Heike Abendroth, Dardan Uka, Mimoza Hoti, Jin Wang, Mikel Zaratiegui and 1 more

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 52 citations in OpenAlex.

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  18. Optimization of the CRISPR/Cas9 system usingmicroPublication biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

María Rodríguez-LópezResearch Department of Genetics, Evolution and Environment, University College London, London, UK.ORCID 0000-0002-2066-0589
Cristina CotobalResearch Department of Genetics, Evolution and Environment, University College London, London, UK.ORCID 0000-0002-5877-2228
Oscar Fernández-SánchezResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
Natalia Borbarán BravoResearch Department of Genetics, Evolution and Environment, University College London, London, UK.ORCID 0000-0001-5987-3023
Risky OktrianiResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
Heike AbendrothResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
Dardan UkaResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
Mimoza HotiResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
Jin WangResearch Department of Genetics, Evolution and Environment, University College London, London, UK.
Mikel ZaratieguiDepartment of Molecular Biology and Biochemistry, Rutgers University, Piscataway, USA.
Jürg BählerResearch Department of Genetics, Evolution and Environment, University College London, London, UK.ORCID 0000-0003-4036-1532
University of Namur · BERutgers, The State University of New Jersey · US

Funding

The cross-regulation of host DNA replication and LTR RetrotransposonsR01GM105831 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI ZARATIEGUI BIURRUN, MIGUEL ANGEL · 2014 to 2018
$1.5M
NIGMS NIH HHS R01 GM105831Wellcome TrustWellcome Trust 095598
6 · The paper itself

Abstract

In the fission yeast

Indexed as

CRISPR-Cas9gene deletiongenome editingmutagenesisPCR primer designsgRNAS. pombe

Identifiers

PMID28612052
PMCPMC5445975
OpenAlexW2552277245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.