Evidence map›Paper›PMID 28612001›Full record

ReviewSkin appendage disorders2017

Botulinum Toxin Off-Label Use in Dermatology: A Review.

Anna Campanati, Emanuela Martina, Katia Giuliodori, Veronica Consales, Ivan Bobyr, Annamaria Offidani

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Skin appendage disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05403710 recruitingnot on this mapstarted 2022, after this paper: background citation

Targeting Nociceptors in Hidradenitis Suppurativa

TypeobservationalSponsorUniversity of Massachusetts, WorcesterRan2022 to 2028Enrolled20ConditionsHidradenitis Suppurativa, HyperhidrosisArmsBotulinum toxin
NCT07756346 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Botulinum Toxin Blockade of Neuronal Signals to Immune Cells as a Novel Treatment for Hidradenitis Suppurativa

TypeinterventionalSponsorUniversity of Massachusetts, WorcesterRan2026 to 2029Enrolled40ConditionsHidradenitis Suppurativa (HS)ArmsBotulinum Toxin A (Allergan, Inc, Irvine CA), Placebo
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. IntramuscularDermatology reports · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. [Clinical application and mechanism of botulinum toxin type A in scar treatment].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anna CampanatiDermatology Unit, Department of Clinical and Molecular Sciences, United Hospital of Ancona, Polytechnic Marche University, Ancona, Italy.
Emanuela MartinaDermatology Unit, Department of Clinical and Molecular Sciences, United Hospital of Ancona, Polytechnic Marche University, Ancona, Italy.
Katia GiuliodoriDermatology Unit, Department of Clinical and Molecular Sciences, United Hospital of Ancona, Polytechnic Marche University, Ancona, Italy.
Veronica ConsalesDermatology Unit, Department of Clinical and Molecular Sciences, United Hospital of Ancona, Polytechnic Marche University, Ancona, Italy.
Ivan BobyrDermatology Unit, Department of Clinical and Molecular Sciences, United Hospital of Ancona, Polytechnic Marche University, Ancona, Italy.
Annamaria OffidaniDermatology Unit, Department of Clinical and Molecular Sciences, United Hospital of Ancona, Polytechnic Marche University, Ancona, Italy.
Marche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBotulinum toxin is a neurotoxin produced by the bacterium

objectiveTo review and analyze the possible botulinum toxin off-label applications published.

methodsA retrospective review of the published data was conducted.

conclusionsthis potent drug can lead to several off-label indications of interest for dermatologists. Further clinical trials are still needed to better understand the real efficacy and safety of these applications and to standardize injection and dose protocols.

Indexed as

Botulinum toxinFolds dermatitisHidradenitis suppurativaKeloidsOff-label therapy

Identifiers

PMID28612001
PMCPMC5465664
OpenAlexW2586458289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.