Evidence map›Paper›PMID 28611846›Full record

ArticleStem cells international2017

Safety of Allogeneic Canine Adipose Tissue-Derived Mesenchymal Stem Cell Intraspinal Transplantation in Dogs with Chronic Spinal Cord Injury.

Cláudia Cardoso Maciel Escalhão, Isalira Peroba Ramos, Camila Hochman-Mendez, Tais Hanae Kasai Brunswick, Sergio Augusto Lopes Souza, Bianca Gutfilen, Regina Coeli Dos Santos Goldenberg, Tatiana Coelho-Sampaio

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

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  9. The Use ofMethods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. An Outstanding Role of Adipose Tissue in Canine Stem Cell Therapy.Animals : an open access journal from MDPI · 2022
    Review
  11. Article
  12. Current Concepts of Stem Cell Therapy for Chronic Spinal Cord Injury.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Cláudia Cardoso Maciel EscalhãoInstitute of Biomedical Sciences, Federal University of Rio de Janeiro, Ave. Carlos Chagas Filho 373, Sala B1-011, Cidade Universitária, Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, Brazil.
Isalira Peroba RamosInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Ave. Carlos Chagas Filho 373, Sala G2-053, Cidade Universitária, Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, Brazil.
Camila Hochman-MendezInstitute of Biomedical Sciences, Federal University of Rio de Janeiro, Ave. Carlos Chagas Filho 373, Sala B1-011, Cidade Universitária, Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, Brazil.
Tais Hanae Kasai BrunswickInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Ave. Carlos Chagas Filho 373, Sala G2-053, Cidade Universitária, Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, Brazil.
Sergio Augusto Lopes SouzaDepartment of Radiology, University Hospital Clementino Fraga Filho and Federal University of Rio de Janeiro, Rua Prof Rodolpho Paulo Rocco, n 255, Sala ss29, Cidade Universitária, Ilha do Fundão, 21941-913 Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-7901-4805
Bianca GutfilenDepartment of Radiology, University Hospital Clementino Fraga Filho and Federal University of Rio de Janeiro, Rua Prof Rodolpho Paulo Rocco, n 255, Sala ss29, Cidade Universitária, Ilha do Fundão, 21941-913 Rio de Janeiro, RJ, Brazil.ORCID 0000-0001-8632-7474
Regina Coeli Dos Santos GoldenbergInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Ave. Carlos Chagas Filho 373, Sala G2-053, Cidade Universitária, Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, Brazil.
Tatiana Coelho-SampaioInstitute of Biomedical Sciences, Federal University of Rio de Janeiro, Ave. Carlos Chagas Filho 373, Sala B1-011, Cidade Universitária, Ilha do Fundão, 21941-590 Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-3020-9580
Universidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a pilot clinical study primarily designed to assess the feasibility and safety of X-ray-guided percutaneous intraspinal injection of allogeneic canine adipose tissue-derived mesenchymal stem cells in dogs with chronic spinal cord injury. Six dogs with chronic paraplegia (≥six months) were intraparenchymally injected with allogeneic cells in the site of lesion. Cells were obtained from subcutaneous adipose tissue of a healthy dog, cultured to passage 3, labeled with

Identifiers

PMID28611846
PMCPMC5458383
OpenAlexW2614672783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.