Evidence map›Paper›PMID 28611783›Full record

ArticleCardiorenal medicine2017

Apolipoprotein L1 Genetic Variants Are Associated with Chronic Kidney Disease but Not with Cardiovascular Disease in a Population Referred for Cardiac Catheterization.

Hanghang Wang, Patrick H Pun, Lydia Kwee, Damian Craig, Carol Haynes, Megan Chryst-Ladd, Laura P Svetkey, Uptal D Patel, Elizabeth R Hauser, Martin R Pollak and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Cardiorenal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Kidney international reports · 2025
    Article
  3. Article
  4. Association ofCirculation · 2019
    Article
  5. Ten years in: APOL1 reaches beyond the kidney.Current opinion in nephrology and hypertension · 2019
    Review
  6. Observational
  7. Circulation. Genomic and precision medicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Hanghang WangDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Patrick H PunDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Lydia KweeDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Damian CraigDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Carol HaynesDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Megan Chryst-LaddDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Laura P SvetkeyDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Uptal D PatelDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Elizabeth R HauserDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Martin R PollakThe Laboratory of Inherited Kidney Disease, Beth Israel Deaconess Medical Center, Boston, MA, USA.
William E KrausDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Svati H ShahDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Duke University · USBeth Israel Deaconess Medical Center · US

Funding

Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI PATEL, UPTAL D · 2012 to 2016
$5.9M
APOL1 variants: Understanding the basis of disparities in rates of kidney diseaseR01MD007092 · NIMHD · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FRIEDMAN, DAVID J, POLLAK, MARTIN R. · 2012 to 2021
$4.3M
6 · The paper itself

Abstract

backgroundWhile the association between

methodsTwo risk variants in

resultsThe previously identified association between

conclusion

Indexed as

Apolipoprotein L1Cardiovascular diseaseChronic kidney diseaseGene polymorphismPopulation genetics

Identifiers

PMID28611783
PMCPMC5465782
OpenAlexW2564878815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.