ArticleFrontiers in systems neuroscience2017
Lack of Responsiveness during the Onset and Offset of Sevoflurane Anesthesia Is Associated with Decreased Awake-Alpha Oscillation Power.
Article in Frontiers in systems neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Oral Dexmedetomidine Promotes Non-rapid Eye Movement Stage 2 Sleep in Humans.Anesthesiology · 2020Trial
- Electroencephalogram monitoring during anesthesia and critical care: a guide for the clinician.Journal of clinical monitoring and computing · 2025Review
- Whole-brain analyses indicate the impairment of posterior integration and thalamo-frontotemporal broadcasting in disorders of consciousness.Human brain mapping · 2023Article
- Quantitative relationship between anteriorization of alpha oscillations and level of general anesthesia.Journal of clinical monitoring and computing · 2023Article
- The posterior dominant rhythm: an electroencephalographic biomarker for cognitive recovery after general anaesthesia.British journal of anaesthesia · 2023Article
- Thalamic T-Type Calcium Channels as Targets for Hypnotics and General Anesthetics.International journal of molecular sciences · 2022Review
- Biophysical Model: A Promising Method in the Study of the Mechanism of Propofol: A Narrative Review.Computational intelligence and neuroscience · 2022Review
- Ketamine induces EEG oscillations that may aid anesthetic state but not dissociation monitoring.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- A Pharmacokinetic and Pharmacodynamic Study of Oral Dexmedetomidine.Anesthesiology · 2020Article
- Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium.Anesthesiology · 2020Article
- Role of electroencephalogram oscillations and the spectrogram in monitoring anaesthesia.BJA education · 2020Review
- The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impact on Translational Neuroimaging.Frontiers in systems neuroscience · 2020Review
- Drug-Specific Models Improve the Performance of an EEG-based Automated Brain-State Prediction System.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019Article
- Electroencephalogram dynamics during general anesthesia predict the later incidence and duration of burst-suppression during cardiopulmonary bypass.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2019Observational
- Delta oscillations phase limit neural activity during sevoflurane anesthesia.Communications biology · 2019Article
- Evoked Alpha Power is Reduced in Disconnected Consciousness During Sleep and Anesthesia.Scientific reports · 2018Article
- Anesthetics Have Different Effects on the Electrocorticographic Spectra of Wild-type and Mitochondrial Mutant Mice.Anesthesiology · 2018Article
- Long-range temporal correlations in the brain distinguish conscious wakefulness from induced unconsciousness.NeuroImage · 2018Article
- Electroencephalographic markers of brain development during sevoflurane anaesthesia in children up to 3 years old.British journal of anaesthesia · 2018Article
- High-energy brain dynamics during anesthesia-induced unconsciousness.Network neuroscience (Cambridge, Mass.) · 2018Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
Abstract
Anesthetic drugs are typically administered to induce altered states of arousal that range from sedation to general anesthesia (GA). Systems neuroscience studies are currently being used to investigate the neural circuit mechanisms of anesthesia-induced altered arousal states. These studies suggest that by disrupting the oscillatory dynamics that are associated with arousal states, anesthesia-induced oscillations are a putative mechanism through which anesthetic drugs produce altered states of arousal. However, an empirical clinical observation is that even at relatively stable anesthetic doses, patients are sometimes intermittently responsive to verbal commands during states of light sedation. During these periods, prominent anesthesia-induced neural oscillations such as slow-delta (0.1-4 Hz) oscillations are notably absent. Neural correlates of intermittent responsiveness during light sedation have been insufficiently investigated. A principled understanding of the neural correlates of intermittent responsiveness may fundamentally advance our understanding of neural dynamics that are essential for maintaining arousal states, and how they are disrupted by anesthetics. Therefore, we performed a high-density (128 channels) electroencephalogram (EEG) study (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.